WHICH CLINICAL PARAMETERS HAVE IMPACT ON OUTCOME IN THE EARLY PHASE OF COMPLICATED INTRA-ABDOMINAL INFECTION? – A PROSPECTIVE STUDY
Purpose: There is still no comprehensive analysis with Bulgarian patients investigating the association between perioperative clinical parameters and final outcome in the early phase of complicated intraabdominal infection. Methods: This single-center prospective study was conducted in the Clinic...
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| Format: | Article |
| Language: | English |
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Trakia University
2024-03-01
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| Series: | Trakia Journal of Sciences |
| Subjects: | |
| Online Access: | http://tru.uni-sz.bg/tsj/Volume%2022,%202024,%20Number%201,%20Series%20Biomedical%20Sciences/8-E.Dimitrov.pdf |
| _version_ | 1797244309324431360 |
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| author | E. Dimitrov G. Minkov E. Enchev Y. Yovtchev |
| author_facet | E. Dimitrov G. Minkov E. Enchev Y. Yovtchev |
| author_sort | E. Dimitrov |
| collection | DOAJ |
| description | Purpose: There is still no comprehensive analysis with Bulgarian patients investigating the association
between perioperative clinical parameters and final outcome in the early phase of complicated intraabdominal infection.
Methods: This single-center prospective study was conducted in the Clinic of Surgical Diseases at the
University Hospital Stara-Zagora for the period November 2018 - August 2021. Before surgery and on
the 3rd postoperative day (POD) we measured axillary temperature (t), systolic blood pressure (SBP),
mean arterial pressure (MAP), respiratory rate (RR), heart rate (HR), mental status and systemic
inflammatory response syndrome (SIRS) in 62 patients with complicated intra-abdominal infections
(cIAIs).
Results: Of the 62 patients, nine died (14.5%). Preoperatively, only MAP successfully discriminated
survivors from non-survivors (p = 0.027), which was confirmed by the ROC Curve analysis (AUROC =
0.731). Postoperatively, almost all of the clinical parameters except axillary temperature (AUROC =
0.573) showed prognostic ability – SBP (AUROC = 0.779) and MAP (AUROC = 0.864) for prediction
of favorable outcome, HR (AUROC = 0.916) and RR (AUROC = 0.935) for prediction of lethal outcome.
Conclusion: All investigated clinical parameters, except for axillary temperature, demonstrated the
ability to predict the final outcome on the 3
rd POD in patients with cIAIs. |
| first_indexed | 2024-04-24T19:08:58Z |
| format | Article |
| id | doaj.art-f160cf25564048b59a6e61d53596ed39 |
| institution | Directory Open Access Journal |
| issn | 1313-3551 |
| language | English |
| last_indexed | 2024-04-24T19:08:58Z |
| publishDate | 2024-03-01 |
| publisher | Trakia University |
| record_format | Article |
| series | Trakia Journal of Sciences |
| spelling | doaj.art-f160cf25564048b59a6e61d53596ed392024-03-26T13:50:20ZengTrakia UniversityTrakia Journal of Sciences1313-35512024-03-01221495710.15547/tjs.2024.01.008WHICH CLINICAL PARAMETERS HAVE IMPACT ON OUTCOME IN THE EARLY PHASE OF COMPLICATED INTRA-ABDOMINAL INFECTION? – A PROSPECTIVE STUDYE. DimitrovG. MinkovE. EnchevY. YovtchevPurpose: There is still no comprehensive analysis with Bulgarian patients investigating the association between perioperative clinical parameters and final outcome in the early phase of complicated intraabdominal infection. Methods: This single-center prospective study was conducted in the Clinic of Surgical Diseases at the University Hospital Stara-Zagora for the period November 2018 - August 2021. Before surgery and on the 3rd postoperative day (POD) we measured axillary temperature (t), systolic blood pressure (SBP), mean arterial pressure (MAP), respiratory rate (RR), heart rate (HR), mental status and systemic inflammatory response syndrome (SIRS) in 62 patients with complicated intra-abdominal infections (cIAIs). Results: Of the 62 patients, nine died (14.5%). Preoperatively, only MAP successfully discriminated survivors from non-survivors (p = 0.027), which was confirmed by the ROC Curve analysis (AUROC = 0.731). Postoperatively, almost all of the clinical parameters except axillary temperature (AUROC = 0.573) showed prognostic ability – SBP (AUROC = 0.779) and MAP (AUROC = 0.864) for prediction of favorable outcome, HR (AUROC = 0.916) and RR (AUROC = 0.935) for prediction of lethal outcome. Conclusion: All investigated clinical parameters, except for axillary temperature, demonstrated the ability to predict the final outcome on the 3 rd POD in patients with cIAIs.http://tru.uni-sz.bg/tsj/Volume%2022,%202024,%20Number%201,%20Series%20Biomedical%20Sciences/8-E.Dimitrov.pdfclinical parameterssirsintra-abdominal infectionsciaisoutcomeprognosis |
| spellingShingle | E. Dimitrov G. Minkov E. Enchev Y. Yovtchev WHICH CLINICAL PARAMETERS HAVE IMPACT ON OUTCOME IN THE EARLY PHASE OF COMPLICATED INTRA-ABDOMINAL INFECTION? – A PROSPECTIVE STUDY Trakia Journal of Sciences clinical parameters sirs intra-abdominal infections ciais outcome prognosis |
| title | WHICH CLINICAL PARAMETERS HAVE IMPACT ON OUTCOME IN THE EARLY PHASE OF COMPLICATED INTRA-ABDOMINAL INFECTION? – A PROSPECTIVE STUDY |
| title_full | WHICH CLINICAL PARAMETERS HAVE IMPACT ON OUTCOME IN THE EARLY PHASE OF COMPLICATED INTRA-ABDOMINAL INFECTION? – A PROSPECTIVE STUDY |
| title_fullStr | WHICH CLINICAL PARAMETERS HAVE IMPACT ON OUTCOME IN THE EARLY PHASE OF COMPLICATED INTRA-ABDOMINAL INFECTION? – A PROSPECTIVE STUDY |
| title_full_unstemmed | WHICH CLINICAL PARAMETERS HAVE IMPACT ON OUTCOME IN THE EARLY PHASE OF COMPLICATED INTRA-ABDOMINAL INFECTION? – A PROSPECTIVE STUDY |
| title_short | WHICH CLINICAL PARAMETERS HAVE IMPACT ON OUTCOME IN THE EARLY PHASE OF COMPLICATED INTRA-ABDOMINAL INFECTION? – A PROSPECTIVE STUDY |
| title_sort | which clinical parameters have impact on outcome in the early phase of complicated intra abdominal infection a prospective study |
| topic | clinical parameters sirs intra-abdominal infections ciais outcome prognosis |
| url | http://tru.uni-sz.bg/tsj/Volume%2022,%202024,%20Number%201,%20Series%20Biomedical%20Sciences/8-E.Dimitrov.pdf |
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