Separation and lipophilicity of some new steroid derivatives in normal- and reversed-phase high performance liquid chromatography
The separation ability and retention of normal and reversed phase HPLC with, respectively, three non-polar and two polar mobile phases, have been studied by measuring the retention constants of a series of newly synthesized estrone derivatives. The separation ability and retention are discussed i...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Association of the Chemical Engineers of Serbia
2011-01-01
|
Series: | Chemical Industry and Chemical Engineering Quarterly |
Subjects: | |
Online Access: | http://www.doiserbia.nb.rs/img/doi/1451-9372/2011/1451-93721100039A.pdf |
_version_ | 1818990673044439040 |
---|---|
author | Ačanski Marijana M. Vujuć Đura N. Jovanović-Šanta Suzana |
author_facet | Ačanski Marijana M. Vujuć Đura N. Jovanović-Šanta Suzana |
author_sort | Ačanski Marijana M. |
collection | DOAJ |
description | The separation ability and retention of normal and reversed phase HPLC with, respectively, three non-polar and two polar mobile phases, have been studied by measuring the retention constants of a series of newly synthesized estrone derivatives. The separation ability and retention are discussed in terms of the nature of the solute, eluent and stationary phase. Good correlation was found between the retention constants log k0 of newly synthesized estrone derivatives obtained on C-18 column and log P calculated by different methods. |
first_indexed | 2024-12-20T19:58:06Z |
format | Article |
id | doaj.art-f16d2587352a47c59c518dab01c7f44e |
institution | Directory Open Access Journal |
issn | 1451-9372 |
language | English |
last_indexed | 2024-12-20T19:58:06Z |
publishDate | 2011-01-01 |
publisher | Association of the Chemical Engineers of Serbia |
record_format | Article |
series | Chemical Industry and Chemical Engineering Quarterly |
spelling | doaj.art-f16d2587352a47c59c518dab01c7f44e2022-12-21T19:28:07ZengAssociation of the Chemical Engineers of SerbiaChemical Industry and Chemical Engineering Quarterly1451-93722011-01-0117453554210.2298/CICEQ110506039ASeparation and lipophilicity of some new steroid derivatives in normal- and reversed-phase high performance liquid chromatographyAčanski Marijana M.Vujuć Đura N.Jovanović-Šanta SuzanaThe separation ability and retention of normal and reversed phase HPLC with, respectively, three non-polar and two polar mobile phases, have been studied by measuring the retention constants of a series of newly synthesized estrone derivatives. The separation ability and retention are discussed in terms of the nature of the solute, eluent and stationary phase. Good correlation was found between the retention constants log k0 of newly synthesized estrone derivatives obtained on C-18 column and log P calculated by different methods.http://www.doiserbia.nb.rs/img/doi/1451-9372/2011/1451-93721100039A.pdfcolumn liquid chromatographysteroidsretention behaviourcorrelation analysis |
spellingShingle | Ačanski Marijana M. Vujuć Đura N. Jovanović-Šanta Suzana Separation and lipophilicity of some new steroid derivatives in normal- and reversed-phase high performance liquid chromatography Chemical Industry and Chemical Engineering Quarterly column liquid chromatography steroids retention behaviour correlation analysis |
title | Separation and lipophilicity of some new steroid derivatives in normal- and reversed-phase high performance liquid chromatography |
title_full | Separation and lipophilicity of some new steroid derivatives in normal- and reversed-phase high performance liquid chromatography |
title_fullStr | Separation and lipophilicity of some new steroid derivatives in normal- and reversed-phase high performance liquid chromatography |
title_full_unstemmed | Separation and lipophilicity of some new steroid derivatives in normal- and reversed-phase high performance liquid chromatography |
title_short | Separation and lipophilicity of some new steroid derivatives in normal- and reversed-phase high performance liquid chromatography |
title_sort | separation and lipophilicity of some new steroid derivatives in normal and reversed phase high performance liquid chromatography |
topic | column liquid chromatography steroids retention behaviour correlation analysis |
url | http://www.doiserbia.nb.rs/img/doi/1451-9372/2011/1451-93721100039A.pdf |
work_keys_str_mv | AT acanskimarijanam separationandlipophilicityofsomenewsteroidderivativesinnormalandreversedphasehighperformanceliquidchromatography AT vujucđuran separationandlipophilicityofsomenewsteroidderivativesinnormalandreversedphasehighperformanceliquidchromatography AT jovanovicsantasuzana separationandlipophilicityofsomenewsteroidderivativesinnormalandreversedphasehighperformanceliquidchromatography |