Separation and lipophilicity of some new steroid derivatives in normal- and reversed-phase high performance liquid chromatography

The separation ability and retention of normal and reversed phase HPLC with, respectively, three non-polar and two polar mobile phases, have been studied by measuring the retention constants of a series of newly synthesized estrone derivatives. The separation ability and retention are discussed i...

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Main Authors: Ačanski Marijana M., Vujuć Đura N., Jovanović-Šanta Suzana
Format: Article
Language:English
Published: Association of the Chemical Engineers of Serbia 2011-01-01
Series:Chemical Industry and Chemical Engineering Quarterly
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/1451-9372/2011/1451-93721100039A.pdf
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author Ačanski Marijana M.
Vujuć Đura N.
Jovanović-Šanta Suzana
author_facet Ačanski Marijana M.
Vujuć Đura N.
Jovanović-Šanta Suzana
author_sort Ačanski Marijana M.
collection DOAJ
description The separation ability and retention of normal and reversed phase HPLC with, respectively, three non-polar and two polar mobile phases, have been studied by measuring the retention constants of a series of newly synthesized estrone derivatives. The separation ability and retention are discussed in terms of the nature of the solute, eluent and stationary phase. Good correlation was found between the retention constants log k0 of newly synthesized estrone derivatives obtained on C-18 column and log P calculated by different methods.
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spelling doaj.art-f16d2587352a47c59c518dab01c7f44e2022-12-21T19:28:07ZengAssociation of the Chemical Engineers of SerbiaChemical Industry and Chemical Engineering Quarterly1451-93722011-01-0117453554210.2298/CICEQ110506039ASeparation and lipophilicity of some new steroid derivatives in normal- and reversed-phase high performance liquid chromatographyAčanski Marijana M.Vujuć Đura N.Jovanović-Šanta SuzanaThe separation ability and retention of normal and reversed phase HPLC with, respectively, three non-polar and two polar mobile phases, have been studied by measuring the retention constants of a series of newly synthesized estrone derivatives. The separation ability and retention are discussed in terms of the nature of the solute, eluent and stationary phase. Good correlation was found between the retention constants log k0 of newly synthesized estrone derivatives obtained on C-18 column and log P calculated by different methods.http://www.doiserbia.nb.rs/img/doi/1451-9372/2011/1451-93721100039A.pdfcolumn liquid chromatographysteroidsretention behaviourcorrelation analysis
spellingShingle Ačanski Marijana M.
Vujuć Đura N.
Jovanović-Šanta Suzana
Separation and lipophilicity of some new steroid derivatives in normal- and reversed-phase high performance liquid chromatography
Chemical Industry and Chemical Engineering Quarterly
column liquid chromatography
steroids
retention behaviour
correlation analysis
title Separation and lipophilicity of some new steroid derivatives in normal- and reversed-phase high performance liquid chromatography
title_full Separation and lipophilicity of some new steroid derivatives in normal- and reversed-phase high performance liquid chromatography
title_fullStr Separation and lipophilicity of some new steroid derivatives in normal- and reversed-phase high performance liquid chromatography
title_full_unstemmed Separation and lipophilicity of some new steroid derivatives in normal- and reversed-phase high performance liquid chromatography
title_short Separation and lipophilicity of some new steroid derivatives in normal- and reversed-phase high performance liquid chromatography
title_sort separation and lipophilicity of some new steroid derivatives in normal and reversed phase high performance liquid chromatography
topic column liquid chromatography
steroids
retention behaviour
correlation analysis
url http://www.doiserbia.nb.rs/img/doi/1451-9372/2011/1451-93721100039A.pdf
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AT jovanovicsantasuzana separationandlipophilicityofsomenewsteroidderivativesinnormalandreversedphasehighperformanceliquidchromatography