An Overview of Tissue Engineering as an Alternative for Toxicity Assessment
Tissue engineering is a multidisciplinary field that combines aspects of biology, material sciences, engineering and medicine - the ultimate goal being able to fabricate replacement tissues and/or organs for an ageing population. However, parallel to this milestone, is the exploitation of the biomim...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2016-02-01
|
| Series: | Journal of Pharmacy & Pharmaceutical Sciences |
| Online Access: | https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/26014 |
| _version_ | 1797718856620310528 |
|---|---|
| author | Mathew Garrod David Yi San Chau |
| author_facet | Mathew Garrod David Yi San Chau |
| author_sort | Mathew Garrod |
| collection | DOAJ |
| description | Tissue engineering is a multidisciplinary field that combines aspects of biology, material sciences, engineering and medicine - the ultimate goal being able to fabricate replacement tissues and/or organs for an ageing population. However, parallel to this milestone, is the exploitation of the biomimetic constructs as feasible alternatives to in vivo/ex vivo toxicity testing models due to their accurate representation of innate tissue and organs. Herein, we summarise a range of concepts within tissue engineering with a particular emphasis on biological material selection and implications to animal testing.
This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page. |
| first_indexed | 2024-03-12T08:56:18Z |
| format | Article |
| id | doaj.art-f16d5303d2f9486db651cd7fcc163b17 |
| institution | Directory Open Access Journal |
| issn | 1482-1826 |
| language | English |
| last_indexed | 2024-03-12T08:56:18Z |
| publishDate | 2016-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Journal of Pharmacy & Pharmaceutical Sciences |
| spelling | doaj.art-f16d5303d2f9486db651cd7fcc163b172023-09-02T16:01:41ZengFrontiers Media S.A.Journal of Pharmacy & Pharmaceutical Sciences1482-18262016-02-0119110.18433/J35P6PAn Overview of Tissue Engineering as an Alternative for Toxicity AssessmentMathew Garrod0David Yi San Chau1The Research Centre in Topical Drug Delivery and Toxicology, Department of Pharmacy, Pharmacology and Postgraduate Medicine, School of Life and Medical Sciences, University of Hertfordshire, College Lane, Hatfield, UK.The Research Centre in Topical Drug Delivery and Toxicology, Department of Pharmacy, Pharmacology and Postgraduate Medicine, School of Life and Medical Sciences, University of Hertfordshire, College Lane, Hatfield, UK.Tissue engineering is a multidisciplinary field that combines aspects of biology, material sciences, engineering and medicine - the ultimate goal being able to fabricate replacement tissues and/or organs for an ageing population. However, parallel to this milestone, is the exploitation of the biomimetic constructs as feasible alternatives to in vivo/ex vivo toxicity testing models due to their accurate representation of innate tissue and organs. Herein, we summarise a range of concepts within tissue engineering with a particular emphasis on biological material selection and implications to animal testing. This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page.https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/26014 |
| spellingShingle | Mathew Garrod David Yi San Chau An Overview of Tissue Engineering as an Alternative for Toxicity Assessment Journal of Pharmacy & Pharmaceutical Sciences |
| title | An Overview of Tissue Engineering as an Alternative for Toxicity Assessment |
| title_full | An Overview of Tissue Engineering as an Alternative for Toxicity Assessment |
| title_fullStr | An Overview of Tissue Engineering as an Alternative for Toxicity Assessment |
| title_full_unstemmed | An Overview of Tissue Engineering as an Alternative for Toxicity Assessment |
| title_short | An Overview of Tissue Engineering as an Alternative for Toxicity Assessment |
| title_sort | overview of tissue engineering as an alternative for toxicity assessment |
| url | https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/26014 |
| work_keys_str_mv | AT mathewgarrod anoverviewoftissueengineeringasanalternativefortoxicityassessment AT davidyisanchau anoverviewoftissueengineeringasanalternativefortoxicityassessment AT mathewgarrod overviewoftissueengineeringasanalternativefortoxicityassessment AT davidyisanchau overviewoftissueengineeringasanalternativefortoxicityassessment |