Radiolysis of myoglobin concentrated gels by protons: specific changes in secondary structure and production of carbon monoxide

Abstract While particle therapy has been used for decades for cancer treatment, there is still a lack of information on the molecular mechanisms of biomolecules radiolysis by accelerated ions. Here, we examine the effects of accelerated protons on highly concentrated native myoglobin, by means of Fo...

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Bibliographic Details
Main Authors: Nicolas Ludwig, Catherine Galindo, Clea Witjaksono, Antoine Danvin, Philippe Peaupardin, Dominique Muller, Tamon Kusumoto, Satoshi Kodaira, Rémi Barillon, Quentin Raffy
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-58378-z