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In this paper, we propose Bees Algorithm (BA) to enhance the performance in estimating the parameters for metabolic pathway data to simulate fermentation pathway for Saccharomyces cerevisiae. However, the parameter estimation of biological processes has always been a challenging task due to the comp...

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Bibliographic Details
Main Authors: Vasileios EFTHYMIOU, Maria KOUTRAKI, Grigoris ANTONIOU
Format: Article
Language:English
Published: Ediciones Universidad de Salamanca 2012-07-01
Series:Advances in Distributed Computing and Artificial Intelligence Journal
Subjects:
Online Access:https://revistas.usal.es/index.php/2255-2863/article/view/10086
Description
Summary:In this paper, we propose Bees Algorithm (BA) to enhance the performance in estimating the parameters for metabolic pathway data to simulate fermentation pathway for Saccharomyces cerevisiae. However, the parameter estimation of biological processes has always been a challenging task due to the complexity and nonlinear equations. Therefore, we present this algorithm as a new approach for parameter estimation for biological interactions to obtain more accurate parameter values. The result shows that BA outperforms other estimation algorithms as it produces the most accurate kinetic parameters, which contributes to the precision of simulated kinetic model.
ISSN:2255-2863