Liquid Crystal Based Binding Assay for Detecting HIV-1 Surface Glycoprotein

Liquid Crystal Based Binding Assay for Detecting HIV-1 Surface Glycoprotein

Surface protein gp-120 of HIV-1 virus plays an important role in the infection of HIV-1, but detection of gp-120 during the early stage of infection is very difficult. Herein, we report a binding bioassay based on an RNA aptamer B40t77, which binds specifically to gp-120. The bioassay is built upon...

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Bibliographic Details
Main Authors: Amna Didar Abbasi, Zakir Hussain, Usman Liaqat, Dooa Arif, Kun-Lin Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Chemistry
Subjects:
liquid crystals
aptamer
gp-120
binding assay
PDMS
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2021.668870/full

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