Tolerance and Adherence of Patients with Chronic Chagas Disease Treated with Benznidazole
ABSTRACT Background: Chagas disease (CD) treatment is commonly associated with a high incidence of adverse effects. It is crucial to study and update these adverse effects to improve the existing knowledge of which drugs to use and to clarify the information presented to patients. Methods: We ana...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Medicina Tropical (SBMT)
2023-01-01
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| Series: | Revista da Sociedade Brasileira de Medicina Tropical |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822023000100305&lng=en&tlng=en |
| _version_ | 1797944938692870144 |
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| author | Cristina Vázquez Elisa García-Vázquez Bartolomé Carrilero Marina Simón Fuensanta Franco María Asunción Iborra Luis Javier Gil-Gallardo Manuel Segovia |
| author_facet | Cristina Vázquez Elisa García-Vázquez Bartolomé Carrilero Marina Simón Fuensanta Franco María Asunción Iborra Luis Javier Gil-Gallardo Manuel Segovia |
| author_sort | Cristina Vázquez |
| collection | DOAJ |
| description | ABSTRACT Background: Chagas disease (CD) treatment is commonly associated with a high incidence of adverse effects. It is crucial to study and update these adverse effects to improve the existing knowledge of which drugs to use and to clarify the information presented to patients. Methods: We analyzed the adverse effects of benznidazole in two cohorts of patients: a large retrospective study and a small prospective study. Results: This large retrospective study described the most and least common adverse effects in our area and characterized our Chagas disease population. This prospective study, along with a close follow-up of the treatment, detected more adverse effects and enhanced the patients’ perception of the disease and treatment. Conclusions: This information is important for preventing non-medical-related withdrawals and for removing baseless fears. Better knowledge of patients could help us provide better care. |
| first_indexed | 2024-04-10T20:46:27Z |
| format | Article |
| id | doaj.art-f1807e617ab4496fa15249f233755058 |
| institution | Directory Open Access Journal |
| issn | 1678-9849 |
| language | English |
| last_indexed | 2024-04-10T20:46:27Z |
| publishDate | 2023-01-01 |
| publisher | Sociedade Brasileira de Medicina Tropical (SBMT) |
| record_format | Article |
| series | Revista da Sociedade Brasileira de Medicina Tropical |
| spelling | doaj.art-f1807e617ab4496fa15249f2337550582023-01-24T07:35:32ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical1678-98492023-01-015610.1590/0037-8682-0384-2022Tolerance and Adherence of Patients with Chronic Chagas Disease Treated with BenznidazoleCristina Vázquezhttps://orcid.org/0000-0002-0762-6108Elisa García-Vázquezhttps://orcid.org/0000-0001-9624-7734Bartolomé Carrilerohttps://orcid.org/0000-0002-0110-603XMarina Simónhttps://orcid.org/0000-0002-6996-5105Fuensanta Francohttps://orcid.org/0000-0001-8306-9326María Asunción Iborrahttps://orcid.org/0000-0002-2550-8500Luis Javier Gil-Gallardohttps://orcid.org/0000-0003-3053-8867Manuel Segoviahttps://orcid.org/0000-0002-3976-103XABSTRACT Background: Chagas disease (CD) treatment is commonly associated with a high incidence of adverse effects. It is crucial to study and update these adverse effects to improve the existing knowledge of which drugs to use and to clarify the information presented to patients. Methods: We analyzed the adverse effects of benznidazole in two cohorts of patients: a large retrospective study and a small prospective study. Results: This large retrospective study described the most and least common adverse effects in our area and characterized our Chagas disease population. This prospective study, along with a close follow-up of the treatment, detected more adverse effects and enhanced the patients’ perception of the disease and treatment. Conclusions: This information is important for preventing non-medical-related withdrawals and for removing baseless fears. Better knowledge of patients could help us provide better care.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822023000100305&lng=en&tlng=enChagasBenznidazoleTrypanosoma cruziToleranceAdherence |
| spellingShingle | Cristina Vázquez Elisa García-Vázquez Bartolomé Carrilero Marina Simón Fuensanta Franco María Asunción Iborra Luis Javier Gil-Gallardo Manuel Segovia Tolerance and Adherence of Patients with Chronic Chagas Disease Treated with Benznidazole Revista da Sociedade Brasileira de Medicina Tropical Chagas Benznidazole Trypanosoma cruzi Tolerance Adherence |
| title | Tolerance and Adherence of Patients with Chronic Chagas Disease Treated with Benznidazole |
| title_full | Tolerance and Adherence of Patients with Chronic Chagas Disease Treated with Benznidazole |
| title_fullStr | Tolerance and Adherence of Patients with Chronic Chagas Disease Treated with Benznidazole |
| title_full_unstemmed | Tolerance and Adherence of Patients with Chronic Chagas Disease Treated with Benznidazole |
| title_short | Tolerance and Adherence of Patients with Chronic Chagas Disease Treated with Benznidazole |
| title_sort | tolerance and adherence of patients with chronic chagas disease treated with benznidazole |
| topic | Chagas Benznidazole Trypanosoma cruzi Tolerance Adherence |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822023000100305&lng=en&tlng=en |
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