Growth hormone secretagogue receptor‐1a mediates ghrelin's effects on attenuating tumour‐induced loss of muscle strength but not muscle mass

Growth hormone secretagogue receptor‐1a mediates ghrelin's effects on attenuating tumour‐induced loss of muscle strength but not muscle mass

Abstract Background Ghrelin may ameliorate cancer cachexia (CC) by preventing anorexia, muscle, and fat loss. However, the mechanisms mediating these effects are not fully understood. This study characterizes the pathways involved in muscle mass and strength loss in the Lewis lung carcinoma (LLC)‐in...

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Bibliographic Details
Main Authors: Haiming Liu, Pu Zang, Ian (In‐gi) Lee, Barbara Anderson, Anthony Christiani, Lena Strait‐Bodey, Beatrice A. Breckheimer, Mackenzie Storie, Alison Tewnion, Kora Krumm, Theresa Li, Brynn Irwin, Jose M. Garcia
Format: Article
Language:English
Published: Wiley 2021-10-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Cachexia
Wasting
Autophagy
Mitochondria
Online Access:https://doi.org/10.1002/jcsm.12743

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