Guillain–Barré syndrome following coronavirus disease vaccine: First report from Nepal

ChAdOx1 nCoV-19 is an effective and well-tolerated coronavirus disease 2019 vaccine. However, rare cases of serious adverse events have been reported with it. We report a patient who did not have active or prior coronavirus disease 2019 infection, who developed Guillain–Barré syndrome 7 days followi...

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Main Authors: Prajjwol Luitel, Bibek Poudel, Devansh Upadhyay, Sujan Paudel, Nishan Tiwari, Bikram Prasad Gajurel, Ragesh Karn, Reema Rajbhandari, Aashish Shrestha, Niraj Gautam, Rajeev Ojha
Format: Article
Language:English
Published: SAGE Publishing 2022-05-01
Series:SAGE Open Medical Case Reports
Online Access:https://doi.org/10.1177/2050313X221100876
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author Prajjwol Luitel
Bibek Poudel
Devansh Upadhyay
Sujan Paudel
Nishan Tiwari
Bikram Prasad Gajurel
Ragesh Karn
Reema Rajbhandari
Aashish Shrestha
Niraj Gautam
Rajeev Ojha
author_facet Prajjwol Luitel
Bibek Poudel
Devansh Upadhyay
Sujan Paudel
Nishan Tiwari
Bikram Prasad Gajurel
Ragesh Karn
Reema Rajbhandari
Aashish Shrestha
Niraj Gautam
Rajeev Ojha
author_sort Prajjwol Luitel
collection DOAJ
description ChAdOx1 nCoV-19 is an effective and well-tolerated coronavirus disease 2019 vaccine. However, rare cases of serious adverse events have been reported with it. We report a patient who did not have active or prior coronavirus disease 2019 infection, who developed Guillain–Barré syndrome 7 days following the first dose of ChAdOx1 nCoV-19 vaccination. He was treated with intravenous immunoglobulin, with stabilization of the disease. Proper monitoring and prompt reporting of such cases are required to ensure the safety of the vaccine.
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spelling doaj.art-f183a7dac63949c799a8897d15d8c99d2022-12-22T02:35:36ZengSAGE PublishingSAGE Open Medical Case Reports2050-313X2022-05-011010.1177/2050313X221100876Guillain–Barré syndrome following coronavirus disease vaccine: First report from NepalPrajjwol Luitel0Bibek Poudel1Devansh Upadhyay2Sujan Paudel3Nishan Tiwari4Bikram Prasad Gajurel5Ragesh Karn6Reema Rajbhandari7Aashish Shrestha8Niraj Gautam9Rajeev Ojha10Tribhuvan University Institute of Medicine, Kathmandu, NepalTribhuvan University Institute of Medicine, Kathmandu, NepalTribhuvan University Institute of Medicine, Kathmandu, NepalTribhuvan University Institute of Medicine, Kathmandu, NepalTribhuvan University Institute of Medicine, Kathmandu, NepalDepartment of Neurology, Tribhuvan University Institute of Medicine, Kathmandu, NepalDepartment of Neurology, Tribhuvan University Institute of Medicine, Kathmandu, NepalDepartment of Neurology, Tribhuvan University Institute of Medicine, Kathmandu, NepalDepartment of Neurology, Tribhuvan University Institute of Medicine, Kathmandu, NepalDepartment of Neurology, Tribhuvan University Institute of Medicine, Kathmandu, NepalDepartment of Neurology, Tribhuvan University Institute of Medicine, Kathmandu, NepalChAdOx1 nCoV-19 is an effective and well-tolerated coronavirus disease 2019 vaccine. However, rare cases of serious adverse events have been reported with it. We report a patient who did not have active or prior coronavirus disease 2019 infection, who developed Guillain–Barré syndrome 7 days following the first dose of ChAdOx1 nCoV-19 vaccination. He was treated with intravenous immunoglobulin, with stabilization of the disease. Proper monitoring and prompt reporting of such cases are required to ensure the safety of the vaccine.https://doi.org/10.1177/2050313X221100876
spellingShingle Prajjwol Luitel
Bibek Poudel
Devansh Upadhyay
Sujan Paudel
Nishan Tiwari
Bikram Prasad Gajurel
Ragesh Karn
Reema Rajbhandari
Aashish Shrestha
Niraj Gautam
Rajeev Ojha
Guillain–Barré syndrome following coronavirus disease vaccine: First report from Nepal
SAGE Open Medical Case Reports
title Guillain–Barré syndrome following coronavirus disease vaccine: First report from Nepal
title_full Guillain–Barré syndrome following coronavirus disease vaccine: First report from Nepal
title_fullStr Guillain–Barré syndrome following coronavirus disease vaccine: First report from Nepal
title_full_unstemmed Guillain–Barré syndrome following coronavirus disease vaccine: First report from Nepal
title_short Guillain–Barré syndrome following coronavirus disease vaccine: First report from Nepal
title_sort guillain barre syndrome following coronavirus disease vaccine first report from nepal
url https://doi.org/10.1177/2050313X221100876
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