Dynamic contrast-enhanced computed tomography to assess early activity of cetuximab in squamous cell carcinoma of the head and neck
Background. Cetuximab, a monoclonal antibody targeting the Epidermal Growth Factor Receptor (EGFR), has demonstrated activity in various tumor types. Using dynamic contrast-enhanced computed tomography (DCE-CT), we investigated the early activity of cetuximab monotherapy in previously untreated pati...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Sciendo
2015-03-01
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| Series: | Radiology and Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.2478/raon-2014-0030 |
| _version_ | 1818596996917755904 |
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| author | Schmitz Sandra Rommel Denis Michoux Nicolas Lhommel Renaud Hanin François-Xavier Duprez Thierry Machiels Jean-Pascal |
| author_facet | Schmitz Sandra Rommel Denis Michoux Nicolas Lhommel Renaud Hanin François-Xavier Duprez Thierry Machiels Jean-Pascal |
| author_sort | Schmitz Sandra |
| collection | DOAJ |
| description | Background. Cetuximab, a monoclonal antibody targeting the Epidermal Growth Factor Receptor (EGFR), has demonstrated activity in various tumor types. Using dynamic contrast-enhanced computed tomography (DCE-CT), we investigated the early activity of cetuximab monotherapy in previously untreated patients with squamous cell carcinoma of the head and neck (SCCHN). |
| first_indexed | 2024-12-16T11:40:47Z |
| format | Article |
| id | doaj.art-f18b23c1dc6a45a18a7cb48288512b75 |
| institution | Directory Open Access Journal |
| issn | 1581-3207 |
| language | English |
| last_indexed | 2024-12-16T11:40:47Z |
| publishDate | 2015-03-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Radiology and Oncology |
| spelling | doaj.art-f18b23c1dc6a45a18a7cb48288512b752022-12-21T22:32:57ZengSciendoRadiology and Oncology1581-32072015-03-01491172510.2478/raon-2014-0030Dynamic contrast-enhanced computed tomography to assess early activity of cetuximab in squamous cell carcinoma of the head and neckSchmitz Sandra0Rommel Denis1Michoux Nicolas2Lhommel Renaud3Hanin François-Xavier4Duprez Thierry5Machiels Jean-Pascal6Department of Medical Oncology and Head and Neck Surgery, Cliniques Universitaires Saint-Luc and Institut de Recherche Clinique et Expérimentale (Pole MIRO), Université Catholique de Louvain, Brussels, BelgiumDepartment of Medical Imaging and Radiology, Cliniques Universitaires Saint-Luc and Institut de Recherche Clinique et Expérimentale (Pole IMAG), Université Catholique de Louvain, Brussels, BelgiumDepartment of Medical Imaging and Radiology, Cliniques Universitaires Saint-Luc and Institut de Recherche Clinique et Expérimentale (Pole IMAG), Université Catholique de Louvain, Brussels, BelgiumDepartment of Nuclear Medicine, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, BelgiumDepartment of Nuclear Medicine, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, BelgiumDepartment of Medical Imaging and Radiology, Cliniques Universitaires Saint-Luc and Institut de Recherche Clinique et Expérimentale (Pole IMAG), Université Catholique de Louvain, Brussels, BelgiumDepartment of Medical Oncology and Head and Neck Surgery, Cliniques Universitaires Saint-Luc and Institut de Recherche Clinique et Expérimentale (Pole MIRO), Université Catholique de Louvain, Brussels, BelgiumBackground. Cetuximab, a monoclonal antibody targeting the Epidermal Growth Factor Receptor (EGFR), has demonstrated activity in various tumor types. Using dynamic contrast-enhanced computed tomography (DCE-CT), we investigated the early activity of cetuximab monotherapy in previously untreated patients with squamous cell carcinoma of the head and neck (SCCHN).https://doi.org/10.2478/raon-2014-0030cetuximabhead and neck cancerperfusiondce-ct |
| spellingShingle | Schmitz Sandra Rommel Denis Michoux Nicolas Lhommel Renaud Hanin François-Xavier Duprez Thierry Machiels Jean-Pascal Dynamic contrast-enhanced computed tomography to assess early activity of cetuximab in squamous cell carcinoma of the head and neck Radiology and Oncology cetuximab head and neck cancer perfusion dce-ct |
| title | Dynamic contrast-enhanced computed tomography to assess early activity of cetuximab in squamous cell carcinoma of the head and neck |
| title_full | Dynamic contrast-enhanced computed tomography to assess early activity of cetuximab in squamous cell carcinoma of the head and neck |
| title_fullStr | Dynamic contrast-enhanced computed tomography to assess early activity of cetuximab in squamous cell carcinoma of the head and neck |
| title_full_unstemmed | Dynamic contrast-enhanced computed tomography to assess early activity of cetuximab in squamous cell carcinoma of the head and neck |
| title_short | Dynamic contrast-enhanced computed tomography to assess early activity of cetuximab in squamous cell carcinoma of the head and neck |
| title_sort | dynamic contrast enhanced computed tomography to assess early activity of cetuximab in squamous cell carcinoma of the head and neck |
| topic | cetuximab head and neck cancer perfusion dce-ct |
| url | https://doi.org/10.2478/raon-2014-0030 |
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