The Role of Iron, Its Metabolism and Ferroptosis in Traumatic Brain Injury

The Role of Iron, Its Metabolism and Ferroptosis in Traumatic Brain Injury

Traumatic brain injury (TBI) is a structural and physiological disruption of brain function caused by external forces. It is a major cause of death and disability for patients worldwide. TBI includes both primary and secondary impairments. Iron overload and ferroptosis highly involved in the pathoph...

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Bibliographic Details
Main Authors: Sicheng Tang, Pan Gao, Hanmin Chen, Xiangyue Zhou, Yibo Ou, Yue He
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
iron
ferroptosis
traumatic brain injury
iron metabolic disorder
iron chelator
reactive oxygen species
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2020.590789/full

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