Evolution of protein-coupled RNA dynamics during hierarchical assembly of ribosomal complexes
Ribosomes assemble through the hierarchical addition of proteins to a ribosomal RNA scaffold. Here the authors use three-color single-molecule FRET to show how the dynamics of the rRNA dictate the order in which multiple proteins assemble on the 5′ domain of the E. coli 16S rRNA.
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2017-09-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-017-00536-1 |
| _version_ | 1818682440888090624 |
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| author | Sanjaya C. Abeysirigunawardena Hajin Kim Jonathan Lai Kaushik Ragunathan Mollie C. Rappé Zaida Luthey-Schulten Taekjip Ha Sarah A. Woodson |
| author_facet | Sanjaya C. Abeysirigunawardena Hajin Kim Jonathan Lai Kaushik Ragunathan Mollie C. Rappé Zaida Luthey-Schulten Taekjip Ha Sarah A. Woodson |
| author_sort | Sanjaya C. Abeysirigunawardena |
| collection | DOAJ |
| description | Ribosomes assemble through the hierarchical addition of proteins to a ribosomal RNA scaffold. Here the authors use three-color single-molecule FRET to show how the dynamics of the rRNA dictate the order in which multiple proteins assemble on the 5′ domain of the E. coli 16S rRNA. |
| first_indexed | 2024-12-17T10:18:53Z |
| format | Article |
| id | doaj.art-f192a5c8e0dd4953a26b536e8ef4f6f9 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-17T10:18:53Z |
| publishDate | 2017-09-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-f192a5c8e0dd4953a26b536e8ef4f6f92022-12-21T21:52:51ZengNature PortfolioNature Communications2041-17232017-09-01811910.1038/s41467-017-00536-1Evolution of protein-coupled RNA dynamics during hierarchical assembly of ribosomal complexesSanjaya C. Abeysirigunawardena0Hajin Kim1Jonathan Lai2Kaushik Ragunathan3Mollie C. Rappé4Zaida Luthey-Schulten5Taekjip Ha6Sarah A. Woodson7T.C. Jenkins Department of Biophysics, Johns Hopkins UniversitySchool of Life Sciences, Ulsan National Institute of Science and TechnologyDepartment of Chemistry, University of Illinois at Urbana-ChampaignDepartment of Physics, Center for the Physics of Living Cells and Institute for Genomic Biology, University of Illinois at Urbana-ChampaignT.C. Jenkins Department of Biophysics, Johns Hopkins UniversityDepartment of Chemistry, University of Illinois at Urbana-ChampaignT.C. Jenkins Department of Biophysics, Johns Hopkins UniversityT.C. Jenkins Department of Biophysics, Johns Hopkins UniversityRibosomes assemble through the hierarchical addition of proteins to a ribosomal RNA scaffold. Here the authors use three-color single-molecule FRET to show how the dynamics of the rRNA dictate the order in which multiple proteins assemble on the 5′ domain of the E. coli 16S rRNA.https://doi.org/10.1038/s41467-017-00536-1 |
| spellingShingle | Sanjaya C. Abeysirigunawardena Hajin Kim Jonathan Lai Kaushik Ragunathan Mollie C. Rappé Zaida Luthey-Schulten Taekjip Ha Sarah A. Woodson Evolution of protein-coupled RNA dynamics during hierarchical assembly of ribosomal complexes Nature Communications |
| title | Evolution of protein-coupled RNA dynamics during hierarchical assembly of ribosomal complexes |
| title_full | Evolution of protein-coupled RNA dynamics during hierarchical assembly of ribosomal complexes |
| title_fullStr | Evolution of protein-coupled RNA dynamics during hierarchical assembly of ribosomal complexes |
| title_full_unstemmed | Evolution of protein-coupled RNA dynamics during hierarchical assembly of ribosomal complexes |
| title_short | Evolution of protein-coupled RNA dynamics during hierarchical assembly of ribosomal complexes |
| title_sort | evolution of protein coupled rna dynamics during hierarchical assembly of ribosomal complexes |
| url | https://doi.org/10.1038/s41467-017-00536-1 |
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