Validation of a liquid chromatographic method for determination of related substances in a candidate certified reference material of captopril

Validation of a liquid chromatographic method for determination of related substances in a candidate certified reference material of captopril

This paper describes the validation of a reversed-phase high performance liquid chromatography method (RP-HPLC) with diode array detection (DAD) for determination of related substances (impurities from organic synthesis and degradation products) of captopril according to the Brazilian Pharmacopeia I...

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Bibliographic Details
Main Authors: Raquel Nogueira, Wagner Wollinger, Thaís Elias da Silva, Leonardo Mesquita de Oliveira, Eliane Cristina Pires do Rego, Gabriela Fernandes Moreira, Juliano Smanioto Barin, Luciane Varini Laporta, Márcia Foster Mesko, Celso Figueiredo Bittencourt, Janaína Marques Rodrigues, Valnei Smarçaro da Cunha
Format: Article
Language:English
Published: Universidade de São Paulo 2011-06-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Captopril
Medicamentos
Cromatografia líquida de alta eficiência
Medicines
High performance liquid chromatography
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000200016

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