Association between hypertension and prognosis of patients with COVID-19: A systematic review and meta-analysis
Background To investigate the association between hypertension and clinical outcomes, including in-hospital mortality, intensive care unit (ICU) admission, and invasive ventilation in patients with coronavirus disease 2019 (COVID-19) pneumonia. Methods We implemented a systematic search of PubMed fo...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2022-07-01
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| Series: | Clinical and Experimental Hypertension |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/10641963.2022.2071914 |
| _version_ | 1797681131607293952 |
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| author | Zhe Qian Zhuohong Li Jie Peng Qiqing Gao Shaohang Cai Xuwen Xu |
| author_facet | Zhe Qian Zhuohong Li Jie Peng Qiqing Gao Shaohang Cai Xuwen Xu |
| author_sort | Zhe Qian |
| collection | DOAJ |
| description | Background To investigate the association between hypertension and clinical outcomes, including in-hospital mortality, intensive care unit (ICU) admission, and invasive ventilation in patients with coronavirus disease 2019 (COVID-19) pneumonia. Methods We implemented a systematic search of PubMed for articles that assessed clinical outcomes of hypertensive patients infected with SARS-CoV-2. The primary outcomes evaluated included: in-hospital mortality, ICU admission, and the use of invasive ventilation. Results A total of 18 studies were included, involving 13,293 patients and covering from January 25, 2020, to April 20, 2020. The relationship between hypertension and prognosis in COVID-19 patients was evaluated. Results showed that hypertension was a risk factor for in-hospital mortality in COVID-19 patients (RR: 2.20, 95% CI, 1.83–2.65, P < .001). Moreover, patients with hypertension were more likely to be admitted to ICU (RR: 1.86, 95% CI, 1.13–3.07, P = .001) and to use invasive ventilation (RR: 2.99, 95% CI, 1.73–5.17, P < .001). Conclusions Among COVID-19 patients, those combined with hypertension had a significantly higher risk of in-hospital deaths, admission to ICU, and need for invasive ventilation. |
| first_indexed | 2024-03-11T23:40:25Z |
| format | Article |
| id | doaj.art-f19a3a58f74a4438a1b070453f8fd324 |
| institution | Directory Open Access Journal |
| issn | 1064-1963 1525-6006 |
| language | English |
| last_indexed | 2024-03-11T23:40:25Z |
| publishDate | 2022-07-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Clinical and Experimental Hypertension |
| spelling | doaj.art-f19a3a58f74a4438a1b070453f8fd3242023-09-19T16:04:07ZengTaylor & Francis GroupClinical and Experimental Hypertension1064-19631525-60062022-07-0144545145810.1080/10641963.2022.20719142071914Association between hypertension and prognosis of patients with COVID-19: A systematic review and meta-analysisZhe Qian0Zhuohong Li1Jie Peng2Qiqing Gao3Shaohang Cai4Xuwen Xu5Nanfang Hospital, Southern Medical UniversityNanfang Hospital, Southern Medical UniversityNanfang Hospital, Southern Medical UniversityNanfang Hospital, Southern Medical UniversityNanfang Hospital, Southern Medical UniversityNanfang Hospital, Southern Medical UniversityBackground To investigate the association between hypertension and clinical outcomes, including in-hospital mortality, intensive care unit (ICU) admission, and invasive ventilation in patients with coronavirus disease 2019 (COVID-19) pneumonia. Methods We implemented a systematic search of PubMed for articles that assessed clinical outcomes of hypertensive patients infected with SARS-CoV-2. The primary outcomes evaluated included: in-hospital mortality, ICU admission, and the use of invasive ventilation. Results A total of 18 studies were included, involving 13,293 patients and covering from January 25, 2020, to April 20, 2020. The relationship between hypertension and prognosis in COVID-19 patients was evaluated. Results showed that hypertension was a risk factor for in-hospital mortality in COVID-19 patients (RR: 2.20, 95% CI, 1.83–2.65, P < .001). Moreover, patients with hypertension were more likely to be admitted to ICU (RR: 1.86, 95% CI, 1.13–3.07, P = .001) and to use invasive ventilation (RR: 2.99, 95% CI, 1.73–5.17, P < .001). Conclusions Among COVID-19 patients, those combined with hypertension had a significantly higher risk of in-hospital deaths, admission to ICU, and need for invasive ventilation.http://dx.doi.org/10.1080/10641963.2022.2071914covid-19epidemiologyhypertensionrespiratory infectionsvirology |
| spellingShingle | Zhe Qian Zhuohong Li Jie Peng Qiqing Gao Shaohang Cai Xuwen Xu Association between hypertension and prognosis of patients with COVID-19: A systematic review and meta-analysis Clinical and Experimental Hypertension covid-19 epidemiology hypertension respiratory infections virology |
| title | Association between hypertension and prognosis of patients with COVID-19: A systematic review and meta-analysis |
| title_full | Association between hypertension and prognosis of patients with COVID-19: A systematic review and meta-analysis |
| title_fullStr | Association between hypertension and prognosis of patients with COVID-19: A systematic review and meta-analysis |
| title_full_unstemmed | Association between hypertension and prognosis of patients with COVID-19: A systematic review and meta-analysis |
| title_short | Association between hypertension and prognosis of patients with COVID-19: A systematic review and meta-analysis |
| title_sort | association between hypertension and prognosis of patients with covid 19 a systematic review and meta analysis |
| topic | covid-19 epidemiology hypertension respiratory infections virology |
| url | http://dx.doi.org/10.1080/10641963.2022.2071914 |
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