Effectiveness of HIIT compared to moderate continuous training in improving vascular parameters in inactive adults
Abstract Background Strong evidence shows that physical inactivity increases the risk of many adverse health conditions, including major non-communicable diseases, such as cardiovascular disease (CVD), metabolic syndrome, and breast and colon cancers, and shortens life expectancy. We aimed to determ...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2019-02-01
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| Series: | Lipids in Health and Disease |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12944-019-0981-z |
| _version_ | 1818148267787026432 |
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| author | Robinson Ramírez-Vélez Paula Andrea Hernández-Quiñones Alejandra Tordecilla-Sanders Cristian Álvarez Rodrigo Ramírez-Campillo Mikel Izquierdo Jorge Enrique Correa-Bautista Antonio Garcia-Hermoso Ronald G. Garcia |
| author_facet | Robinson Ramírez-Vélez Paula Andrea Hernández-Quiñones Alejandra Tordecilla-Sanders Cristian Álvarez Rodrigo Ramírez-Campillo Mikel Izquierdo Jorge Enrique Correa-Bautista Antonio Garcia-Hermoso Ronald G. Garcia |
| author_sort | Robinson Ramírez-Vélez |
| collection | DOAJ |
| description | Abstract Background Strong evidence shows that physical inactivity increases the risk of many adverse health conditions, including major non-communicable diseases, such as cardiovascular disease (CVD), metabolic syndrome, and breast and colon cancers, and shortens life expectancy. We aimed to determine the effects of moderate (MCT)- versus high-intensity interval training (HIT) on vascular function parameters in physically inactive adults. We hypothesized that individualized HIT prescription would improve the vascular function parameters more than the MCT in a greater proportion of individuals. Methods Twenty-one inactive adults were randomly allocated to receive either MCT group (60–75% of their heart rate reserve, [HRR] or HIT group (4 min at 85–95% of peak HRR), 3 days a week for 12 weeks. Vascular function (brachial artery flow-mediated dilation, FMD [%], normalized brachial artery flow-mediated dilation, FMDn [%], aortic pulse wave velocity, PWV [m·s− 1], AIx, augmentation index: aortic and brachial [%]), were measured at baseline and over 12 weeks of training. In order for a participant to be considered a responder to improvements in vascular function parameters (FMDn and PWV), the typical error was calculated in a favorable direction. Results FMD changed by − 1.0% (SE 2.1, d = 0.388) in the MCT group, and + 1.8% (SE 1.8, d = 0.699) in the HIT group (no significant difference between groups: 2.9% [95% CI, − 3.0 to 8.8]. PWV changed by + 0.1 m·s− 1 (SE 0.2, d = 0.087) in the MCT group but decreased by − 0.4 m·s− 1 in the HIT group (SE 0.2, d = 0.497), with significant difference between groups: − 0.4 [95% CI, − 0.2 to − 0.7]. There was not a significant difference in the prevalence of no-responder for FMD (%) between the MCT and HIT groups (66% versus 36%, P = 0.157). Regarding PWV (m·s− 1), an analysis showed that the prevalence of no-responder was 77% (7 cases) in the MCT group and 45% (5 cases) in the HIT group (P = 0.114). Conclusions Under the conditions of the present study, both groups experienced changed in vascular function parameters. Compared to MCT group, HIT is more efficacious for improving FMD and decreasing PWV, in physically inactive adults. Trial registration ClinicalTrials.gov NCT02738385 registered on 23 March 2016. |
| first_indexed | 2024-12-11T12:48:26Z |
| format | Article |
| id | doaj.art-f1a27b375c204c82b1a39dfef83321f4 |
| institution | Directory Open Access Journal |
| issn | 1476-511X |
| language | English |
| last_indexed | 2024-12-11T12:48:26Z |
| publishDate | 2019-02-01 |
| publisher | BMC |
| record_format | Article |
| series | Lipids in Health and Disease |
| spelling | doaj.art-f1a27b375c204c82b1a39dfef83321f42022-12-22T01:06:46ZengBMCLipids in Health and Disease1476-511X2019-02-0118111010.1186/s12944-019-0981-zEffectiveness of HIIT compared to moderate continuous training in improving vascular parameters in inactive adultsRobinson Ramírez-Vélez0Paula Andrea Hernández-Quiñones1Alejandra Tordecilla-Sanders2Cristian Álvarez3Rodrigo Ramírez-Campillo4Mikel Izquierdo5Jorge Enrique Correa-Bautista6Antonio Garcia-Hermoso7Ronald G. Garcia8Centro de Estudios para la Medición de la Actividad Física “CEMA”. Escuela de Medicina y Ciencias de la Salud, Universidad del RosarioGrupo GICAEDS. Programa de Cultura Física, Deporte y Recreación, Universidad Santo TomásCentro de Estudios para la Medición de la Actividad Física “CEMA”. Escuela de Medicina y Ciencias de la Salud, Universidad del RosarioDepartment of Physical Activity Sciences, Universidad de Los LagosResearch Nucleus in Health, Physical Activity and Sports, Universidad de Los LagosDepartment of Health Sciences, Public University of Navarre, CIBER de Fragilidad y Envejecimiento Saludable (CB16/10/00315)Centro de Estudios para la Medición de la Actividad Física “CEMA”. Escuela de Medicina y Ciencias de la Salud, Universidad del RosarioLaboratorio de Ciencias de la Actividad Física, el Deporte y la Salud, Universidad de Santiago de Chile, USACHMartinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical SchoolAbstract Background Strong evidence shows that physical inactivity increases the risk of many adverse health conditions, including major non-communicable diseases, such as cardiovascular disease (CVD), metabolic syndrome, and breast and colon cancers, and shortens life expectancy. We aimed to determine the effects of moderate (MCT)- versus high-intensity interval training (HIT) on vascular function parameters in physically inactive adults. We hypothesized that individualized HIT prescription would improve the vascular function parameters more than the MCT in a greater proportion of individuals. Methods Twenty-one inactive adults were randomly allocated to receive either MCT group (60–75% of their heart rate reserve, [HRR] or HIT group (4 min at 85–95% of peak HRR), 3 days a week for 12 weeks. Vascular function (brachial artery flow-mediated dilation, FMD [%], normalized brachial artery flow-mediated dilation, FMDn [%], aortic pulse wave velocity, PWV [m·s− 1], AIx, augmentation index: aortic and brachial [%]), were measured at baseline and over 12 weeks of training. In order for a participant to be considered a responder to improvements in vascular function parameters (FMDn and PWV), the typical error was calculated in a favorable direction. Results FMD changed by − 1.0% (SE 2.1, d = 0.388) in the MCT group, and + 1.8% (SE 1.8, d = 0.699) in the HIT group (no significant difference between groups: 2.9% [95% CI, − 3.0 to 8.8]. PWV changed by + 0.1 m·s− 1 (SE 0.2, d = 0.087) in the MCT group but decreased by − 0.4 m·s− 1 in the HIT group (SE 0.2, d = 0.497), with significant difference between groups: − 0.4 [95% CI, − 0.2 to − 0.7]. There was not a significant difference in the prevalence of no-responder for FMD (%) between the MCT and HIT groups (66% versus 36%, P = 0.157). Regarding PWV (m·s− 1), an analysis showed that the prevalence of no-responder was 77% (7 cases) in the MCT group and 45% (5 cases) in the HIT group (P = 0.114). Conclusions Under the conditions of the present study, both groups experienced changed in vascular function parameters. Compared to MCT group, HIT is more efficacious for improving FMD and decreasing PWV, in physically inactive adults. Trial registration ClinicalTrials.gov NCT02738385 registered on 23 March 2016.http://link.springer.com/article/10.1186/s12944-019-0981-zAerobic exerciseArterial stiffnessCardiovascular disease preventionEndothelial dysfunctionSedentarism |
| spellingShingle | Robinson Ramírez-Vélez Paula Andrea Hernández-Quiñones Alejandra Tordecilla-Sanders Cristian Álvarez Rodrigo Ramírez-Campillo Mikel Izquierdo Jorge Enrique Correa-Bautista Antonio Garcia-Hermoso Ronald G. Garcia Effectiveness of HIIT compared to moderate continuous training in improving vascular parameters in inactive adults Lipids in Health and Disease Aerobic exercise Arterial stiffness Cardiovascular disease prevention Endothelial dysfunction Sedentarism |
| title | Effectiveness of HIIT compared to moderate continuous training in improving vascular parameters in inactive adults |
| title_full | Effectiveness of HIIT compared to moderate continuous training in improving vascular parameters in inactive adults |
| title_fullStr | Effectiveness of HIIT compared to moderate continuous training in improving vascular parameters in inactive adults |
| title_full_unstemmed | Effectiveness of HIIT compared to moderate continuous training in improving vascular parameters in inactive adults |
| title_short | Effectiveness of HIIT compared to moderate continuous training in improving vascular parameters in inactive adults |
| title_sort | effectiveness of hiit compared to moderate continuous training in improving vascular parameters in inactive adults |
| topic | Aerobic exercise Arterial stiffness Cardiovascular disease prevention Endothelial dysfunction Sedentarism |
| url | http://link.springer.com/article/10.1186/s12944-019-0981-z |
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