Longitudinal characterization of phenotypic profile of T cells in chronic hepatitis B identifies immune markers associated with HBsAg loss

Longitudinal characterization of phenotypic profile of T cells in chronic hepatitis B identifies immune markers associated with HBsAg loss

Background: The current desirable endpoint of treatment against chronic hepatitis B virus infection (cHBV) is to achieve a functional cure, which is defined as HBsAg loss (sAg-L) with or without anti-HBs seroconversion. However, the immunological features that are associated with functional cure hav...

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Bibliographic Details
Main Authors: Shue Xiong, Dan Zhu, Boyun Liang, Mingyue Li, Wen Pan, Junyi He, Hua Wang, Kathrin Sutter, Ulf Dittmer, Mengji Lu, Di Liu, Dongliang Yang, Jia Liu, Xin Zheng
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:EBioMedicine
Subjects:
Chronic HBV infection
Functional cure
HBsAg
T cell phenotype
HBV-specific T cell
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396421002577

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