Age and sex-related differences in epidemiology, treatment, and mortality of patients with ST-segment elevation myocardial infarction in Iran

Introduction: Few studies have investigated the characteristics of patients with ST elevation myocardial infarction (STEMI) according to age and sex in Iran. This study aims to investigate the risk factors profile, treatment, and mortality of STEMI based on age and sex. Methods: From 10th June 2016...

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Main Authors: Mehdi Darabi, Reza Heidari Moghaddam, Farzaneh Godarzi, Sahar Karami, Soraya Siabani, Nahid Salehi
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2023-12-01
Series:Journal of Cardiovascular and Thoracic Research
Subjects:
Online Access:https://jcvtr.tbzmed.ac.ir/PDF/jcvtr-15-210.pdf
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author Mehdi Darabi
Reza Heidari Moghaddam
Farzaneh Godarzi
Sahar Karami
Soraya Siabani
Nahid Salehi
author_facet Mehdi Darabi
Reza Heidari Moghaddam
Farzaneh Godarzi
Sahar Karami
Soraya Siabani
Nahid Salehi
author_sort Mehdi Darabi
collection DOAJ
description Introduction: Few studies have investigated the characteristics of patients with ST elevation myocardial infarction (STEMI) according to age and sex in Iran. This study aims to investigate the risk factors profile, treatment, and mortality of STEMI based on age and sex. Methods: From 10th June 2016 to December 2019 a total of 2816, STEMI patients referred to the Imam Ali heart center of Kermanshah were included in the study. Profile of the risk factors, epidemiology, treatment and 30- day mortality for all cases in the age categories of 18-49, 50-64, and≥65 years were studied. Results: There were 1256 (44.6%) middle-aged STEMI patients, and 2181 (77.45%) were male. The elderly had a longer median door-to-balloon and symptom-to-balloon time and received less primary PCI. In the absence of primary PCI, the rate of 30-day mortality in women was higher than in men, and the mortality rate increased with age. The risk of death in middle-aged women was higher than that of men. Also, in the middle-aged group, after multivariable adjustment, previous bypass surgery, diabetes, and Killip class≥2 was associated with significant increase in the risk of death. Conclusion: The present study showed that young people with STEMI had a high risk of heart failure and anterior infarction compared to the older age groups. Women had more risk factors for STEMI and a higher mortality rate than men. Therefore, there is a need to educate young age groups and women to modify their lifestyles and intervene in the risk factors of heart diseases.
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spelling doaj.art-f1a36931507d405cb017c0092e99ca8a2024-02-03T10:27:21ZengTabriz University of Medical SciencesJournal of Cardiovascular and Thoracic Research2008-51172008-68302023-12-0115421021710.34172/jcvtr.2023.32887jcvtr-32887Age and sex-related differences in epidemiology, treatment, and mortality of patients with ST-segment elevation myocardial infarction in IranMehdi Darabi0Reza Heidari Moghaddam1Farzaneh Godarzi2Sahar Karami3Soraya Siabani4Nahid Salehi5Cardiovascular Research Center, Health Institute, Imam-Ali Hospital, Kermanshah University of Medical Sciences, Kermanshah, IranCardiovascular Research Center, Health Institute, Imam-Ali Hospital, Kermanshah University of Medical Sciences, Kermanshah, IranCardiovascular Research Center, Health Institute, Imam-Ali Hospital, Kermanshah University of Medical Sciences, Kermanshah, IranCardiovascular Research Center, Health Institute, Imam-Ali Hospital, Kermanshah University of Medical Sciences, Kermanshah, IranDepartment of Health Education and Health Promotion, Kermanshah University of Medical Sciences, Kermanshah, IranCardiovascular Research Center, Health Institute, Imam-Ali Hospital, Kermanshah University of Medical Sciences, Kermanshah, IranIntroduction: Few studies have investigated the characteristics of patients with ST elevation myocardial infarction (STEMI) according to age and sex in Iran. This study aims to investigate the risk factors profile, treatment, and mortality of STEMI based on age and sex. Methods: From 10th June 2016 to December 2019 a total of 2816, STEMI patients referred to the Imam Ali heart center of Kermanshah were included in the study. Profile of the risk factors, epidemiology, treatment and 30- day mortality for all cases in the age categories of 18-49, 50-64, and≥65 years were studied. Results: There were 1256 (44.6%) middle-aged STEMI patients, and 2181 (77.45%) were male. The elderly had a longer median door-to-balloon and symptom-to-balloon time and received less primary PCI. In the absence of primary PCI, the rate of 30-day mortality in women was higher than in men, and the mortality rate increased with age. The risk of death in middle-aged women was higher than that of men. Also, in the middle-aged group, after multivariable adjustment, previous bypass surgery, diabetes, and Killip class≥2 was associated with significant increase in the risk of death. Conclusion: The present study showed that young people with STEMI had a high risk of heart failure and anterior infarction compared to the older age groups. Women had more risk factors for STEMI and a higher mortality rate than men. Therefore, there is a need to educate young age groups and women to modify their lifestyles and intervene in the risk factors of heart diseases.https://jcvtr.tbzmed.ac.ir/PDF/jcvtr-15-210.pdfsexmortalitytreatmentstemirisk factors
spellingShingle Mehdi Darabi
Reza Heidari Moghaddam
Farzaneh Godarzi
Sahar Karami
Soraya Siabani
Nahid Salehi
Age and sex-related differences in epidemiology, treatment, and mortality of patients with ST-segment elevation myocardial infarction in Iran
Journal of Cardiovascular and Thoracic Research
sex
mortality
treatment
stemi
risk factors
title Age and sex-related differences in epidemiology, treatment, and mortality of patients with ST-segment elevation myocardial infarction in Iran
title_full Age and sex-related differences in epidemiology, treatment, and mortality of patients with ST-segment elevation myocardial infarction in Iran
title_fullStr Age and sex-related differences in epidemiology, treatment, and mortality of patients with ST-segment elevation myocardial infarction in Iran
title_full_unstemmed Age and sex-related differences in epidemiology, treatment, and mortality of patients with ST-segment elevation myocardial infarction in Iran
title_short Age and sex-related differences in epidemiology, treatment, and mortality of patients with ST-segment elevation myocardial infarction in Iran
title_sort age and sex related differences in epidemiology treatment and mortality of patients with st segment elevation myocardial infarction in iran
topic sex
mortality
treatment
stemi
risk factors
url https://jcvtr.tbzmed.ac.ir/PDF/jcvtr-15-210.pdf
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