Functional role of the type 1 pilus rod structure in mediating host-pathogen interactions
Uropathogenic E. coli (UPEC), which cause urinary tract infections (UTI), utilize type 1 pili, a chaperone usher pathway (CUP) pilus, to cause UTI and colonize the gut. The pilus rod, comprised of repeating FimA subunits, provides a structural scaffold for displaying the tip adhesin, FimH. We solved...
Autores principales: | Caitlin N Spaulding, Henry Louis Schreiber IV, Weili Zheng, Karen W Dodson, Jennie E Hazen, Matt S Conover, Fengbin Wang, Pontus Svenmarker, Areli Luna-Rico, Olivera Francetic, Magnus Andersson, Scott Hultgren, Edward H Egelman |
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Formato: | Artículo |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications Ltd
2018-01-01
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Colección: | eLife |
Materias: | |
Acceso en línea: | https://elifesciences.org/articles/31662 |
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