Candida albicans exhibits heterogeneous and adaptive cytoprotective responses to antifungal compounds

Candida albicans exhibits heterogeneous and adaptive cytoprotective responses to antifungal compounds

Candida albicans, an opportunistic human pathogen, poses a significant threat to human health and is associated with significant socio-economic burden. Current antifungal treatments fail, at least in part, because C. albicans can initiate a strong drug tolerance response that allows some cells to gr...

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Bibliographic Details
Main Authors: Vanessa Dumeaux, Samira Massahi, Van Bettauer, Austin Mottola, Anna Dukovny, Sanny Singh Khurdia, Anna Carolina Borges Pereira Costa, Raha Parvizi Omran, Shawn Simpson, Jinglin Lucy Xie, Malcolm Whiteway, Judith Berman, Michael T Hallett
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-10-01
Series:eLife
Subjects:
Candida albicans
single-cell sequencing
drug tolerance
ribosome assembly stress response
Online Access:https://elifesciences.org/articles/81406

Internet

https://elifesciences.org/articles/81406

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