Diagnosis and Treatment of Refractory Gastroesophageal Reflux Disease (GERD)
Gastroesophageal reflux disease (GERD) was a damage in mucosal layer caused by gastric acid reflux. GERD was found about 10-20% in Western Countries and less in Asia, about 2,6-6,7%. Among different type of GERD, refractory GERD was a problem found in daily clinical practice. This terminology was us...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Interna Publishing
2015-12-01
|
| Series: | The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy |
| Subjects: | |
| Online Access: | http://ina-jghe.com/journal/index.php/jghe/article/view/502/428 |
| _version_ | 1828393247384272896 |
|---|---|
| author | Selfie Marcellus Simadibrata |
| author_facet | Selfie Marcellus Simadibrata |
| author_sort | Selfie |
| collection | DOAJ |
| description | Gastroesophageal reflux disease (GERD) was a damage in mucosal layer caused by gastric acid reflux. GERD was found about 10-20% in Western Countries and less in Asia, about 2,6-6,7%. Among different type of GERD, refractory GERD was a problem found in daily clinical practice. This terminology was used in patients with regurgitation and heartburn symptoms which is not responsive to 8 weeks proton pump inhibitor (PPI) therapy. There were several mechanisms underlying the etiology and pathophysiology of refractory GERD. In general, refractory GERD diagnosis was based on clinical findings, objective endoscopic examination, ambulatory reflux monitoring, and response to antiacid-secretion therapy. Reevaluation of patients compliance should be the first step in refractory GERD management. A further treatment strategies could be started, consist of medical and surgical therapies. A basic clinical knowledge of refractory GERD would help clinician in deciding the best approach for diagnosis and therapy. |
| first_indexed | 2024-12-10T07:34:35Z |
| format | Article |
| id | doaj.art-f1a53277ba1b40e4ba5736ced28ef610 |
| institution | Directory Open Access Journal |
| issn | 1411-4801 2302-8181 |
| language | English |
| last_indexed | 2024-12-10T07:34:35Z |
| publishDate | 2015-12-01 |
| publisher | Interna Publishing |
| record_format | Article |
| series | The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy |
| spelling | doaj.art-f1a53277ba1b40e4ba5736ced28ef6102022-12-22T01:57:27ZengInterna PublishingThe Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy1411-48012302-81812015-12-01163183189Diagnosis and Treatment of Refractory Gastroesophageal Reflux Disease (GERD)Selfie0Marcellus Simadibrata1Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, University of Indonesia/Dr. Cipto Mangunkusumo General National Hospital, JakartaDivision of Gastroenterology, Department of Internal Medicine Faculty of Medicine, University of Indonesia/Dr. Cipto Mangunkusumo Hospital JakartaGastroesophageal reflux disease (GERD) was a damage in mucosal layer caused by gastric acid reflux. GERD was found about 10-20% in Western Countries and less in Asia, about 2,6-6,7%. Among different type of GERD, refractory GERD was a problem found in daily clinical practice. This terminology was used in patients with regurgitation and heartburn symptoms which is not responsive to 8 weeks proton pump inhibitor (PPI) therapy. There were several mechanisms underlying the etiology and pathophysiology of refractory GERD. In general, refractory GERD diagnosis was based on clinical findings, objective endoscopic examination, ambulatory reflux monitoring, and response to antiacid-secretion therapy. Reevaluation of patients compliance should be the first step in refractory GERD management. A further treatment strategies could be started, consist of medical and surgical therapies. A basic clinical knowledge of refractory GERD would help clinician in deciding the best approach for diagnosis and therapy.http://ina-jghe.com/journal/index.php/jghe/article/view/502/428refractory gastroesophageal reflux disease (GERD)proton pump inhibitor (PPI) therapydiagnosistherapyreevaluation |
| spellingShingle | Selfie Marcellus Simadibrata Diagnosis and Treatment of Refractory Gastroesophageal Reflux Disease (GERD) The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy refractory gastroesophageal reflux disease (GERD) proton pump inhibitor (PPI) therapy diagnosis therapy reevaluation |
| title | Diagnosis and Treatment of Refractory Gastroesophageal Reflux Disease (GERD) |
| title_full | Diagnosis and Treatment of Refractory Gastroesophageal Reflux Disease (GERD) |
| title_fullStr | Diagnosis and Treatment of Refractory Gastroesophageal Reflux Disease (GERD) |
| title_full_unstemmed | Diagnosis and Treatment of Refractory Gastroesophageal Reflux Disease (GERD) |
| title_short | Diagnosis and Treatment of Refractory Gastroesophageal Reflux Disease (GERD) |
| title_sort | diagnosis and treatment of refractory gastroesophageal reflux disease gerd |
| topic | refractory gastroesophageal reflux disease (GERD) proton pump inhibitor (PPI) therapy diagnosis therapy reevaluation |
| url | http://ina-jghe.com/journal/index.php/jghe/article/view/502/428 |
| work_keys_str_mv | AT selfie diagnosisandtreatmentofrefractorygastroesophagealrefluxdiseasegerd AT marcellussimadibrata diagnosisandtreatmentofrefractorygastroesophagealrefluxdiseasegerd |