Isolated ascending aorta dilatation is associated with increased risk of abdominal aortic aneurysm
Abstract Background Abdominal aortic aneurysm (AAA) is an asymptomatic condition characterized by progressive dilatation of the aorta. The purpose of this study is to identify important 2D-TTE aortic indices associated with AAA as predictive tools for undiagnosed AAA. Methods In this retrospective s...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2021-04-01
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| Series: | Journal of Cardiothoracic Surgery |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13019-021-01488-w |
| _version_ | 1818590315038113792 |
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| author | Enrique Gallego-Colon Chaim Yosefy Evgenia Cherniavsky Azriel Osherov Vladimir Khalameizer Xavier Piltz Marina Pery Sharon Bruoha Jamal Jafari |
| author_facet | Enrique Gallego-Colon Chaim Yosefy Evgenia Cherniavsky Azriel Osherov Vladimir Khalameizer Xavier Piltz Marina Pery Sharon Bruoha Jamal Jafari |
| author_sort | Enrique Gallego-Colon |
| collection | DOAJ |
| description | Abstract Background Abdominal aortic aneurysm (AAA) is an asymptomatic condition characterized by progressive dilatation of the aorta. The purpose of this study is to identify important 2D-TTE aortic indices associated with AAA as predictive tools for undiagnosed AAA. Methods In this retrospective study, we evaluated the size of the ascending aorta in patients without known valvular diseases or hemodynamic compromise as predictive tool for undiagnosed AAA. We studied the tubular ascending aorta of 170 patients by 2-dimensional transthoracic echocardiography (2D-TTE). Patients were further divided into two groups, 70 patients with AAA and 100 patients without AAA with normal imaging results. Results Dilatation of tubular ascending aorta was measured in patients with AAA compared to the group with absent AAA (37.5 ± 4.8 mm vs. 31.2 ± 3.6 mm, p < 0.001, respectively) and confirmed by computed tomographic (CT) (35.6 ± 5.1 mm vs. 30.8 ± 3.7 mm, p < 0.001, respectively). An increase in tubular ascending aorta size was associated with the presence of AAA by both 2D-TTE and CT (r = 0.40, p < 0.001 and r = 0.37, p < 0.001, respectively). The tubular ascending aorta (D diameter) size of ≥33 mm or ≥ 19 mm/m2 presented with 2–4 times more risk of AAA presence (OR 4.68, CI 2.18–10.25, p = 0.001 or OR 2.63, CI 1.21–5.62, p = 0.02, respectively). In addition, multiple logistic regression analysis identified tubular ascending aorta (OR 1.46, p < 0.001), age (OR 1.09, p = 0.013), gender (OR 0.12, p = 0.002), and LVESD (OR 1.24, p = 0.009) as independent risk factors of AAA presence. Conclusions An increased tubular ascending aortic diameter, measured by 2D-TTE, is associated with the presence of AAA. Routine 2D-TTE screening for silent AAA by means of ascending aorta analysis, may appear useful especially in older patients with a dilated tubular ascending aorta (≥33 mm). |
| first_indexed | 2024-12-16T09:54:35Z |
| format | Article |
| id | doaj.art-f1a71a7e867a40f9b31d1a232b2acd6c |
| institution | Directory Open Access Journal |
| issn | 1749-8090 |
| language | English |
| last_indexed | 2024-12-16T09:54:35Z |
| publishDate | 2021-04-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Cardiothoracic Surgery |
| spelling | doaj.art-f1a71a7e867a40f9b31d1a232b2acd6c2022-12-21T22:35:58ZengBMCJournal of Cardiothoracic Surgery1749-80902021-04-011611810.1186/s13019-021-01488-wIsolated ascending aorta dilatation is associated with increased risk of abdominal aortic aneurysmEnrique Gallego-Colon0Chaim Yosefy1Evgenia Cherniavsky2Azriel Osherov3Vladimir Khalameizer4Xavier Piltz5Marina Pery6Sharon Bruoha7Jamal Jafari8Cardiology Department, Barzilai Medical Center Campus, Barzilai University Medical Center, Ben-Gurion UniversityCardiology Department, Barzilai Medical Center Campus, Barzilai University Medical Center, Ben-Gurion UniversityDepartment of Medical Imaging, Barzilai University Medical Center, Ben-Gurion UniversityCardiology Department, Barzilai Medical Center Campus, Barzilai University Medical Center, Ben-Gurion UniversityCardiology Department, Barzilai Medical Center Campus, Barzilai University Medical Center, Ben-Gurion UniversityDepartment of Medical Imaging, Barzilai University Medical Center, Ben-Gurion UniversityCardiology Department, Barzilai Medical Center Campus, Barzilai University Medical Center, Ben-Gurion UniversityCardiology Department, Barzilai Medical Center Campus, Barzilai University Medical Center, Ben-Gurion UniversityCardiology Department, Barzilai Medical Center Campus, Barzilai University Medical Center, Ben-Gurion UniversityAbstract Background Abdominal aortic aneurysm (AAA) is an asymptomatic condition characterized by progressive dilatation of the aorta. The purpose of this study is to identify important 2D-TTE aortic indices associated with AAA as predictive tools for undiagnosed AAA. Methods In this retrospective study, we evaluated the size of the ascending aorta in patients without known valvular diseases or hemodynamic compromise as predictive tool for undiagnosed AAA. We studied the tubular ascending aorta of 170 patients by 2-dimensional transthoracic echocardiography (2D-TTE). Patients were further divided into two groups, 70 patients with AAA and 100 patients without AAA with normal imaging results. Results Dilatation of tubular ascending aorta was measured in patients with AAA compared to the group with absent AAA (37.5 ± 4.8 mm vs. 31.2 ± 3.6 mm, p < 0.001, respectively) and confirmed by computed tomographic (CT) (35.6 ± 5.1 mm vs. 30.8 ± 3.7 mm, p < 0.001, respectively). An increase in tubular ascending aorta size was associated with the presence of AAA by both 2D-TTE and CT (r = 0.40, p < 0.001 and r = 0.37, p < 0.001, respectively). The tubular ascending aorta (D diameter) size of ≥33 mm or ≥ 19 mm/m2 presented with 2–4 times more risk of AAA presence (OR 4.68, CI 2.18–10.25, p = 0.001 or OR 2.63, CI 1.21–5.62, p = 0.02, respectively). In addition, multiple logistic regression analysis identified tubular ascending aorta (OR 1.46, p < 0.001), age (OR 1.09, p = 0.013), gender (OR 0.12, p = 0.002), and LVESD (OR 1.24, p = 0.009) as independent risk factors of AAA presence. Conclusions An increased tubular ascending aortic diameter, measured by 2D-TTE, is associated with the presence of AAA. Routine 2D-TTE screening for silent AAA by means of ascending aorta analysis, may appear useful especially in older patients with a dilated tubular ascending aorta (≥33 mm).https://doi.org/10.1186/s13019-021-01488-wAbdominal aortic aneurysmAortic dilatationScreeningComputed tomographyTransthoracic echocardiography |
| spellingShingle | Enrique Gallego-Colon Chaim Yosefy Evgenia Cherniavsky Azriel Osherov Vladimir Khalameizer Xavier Piltz Marina Pery Sharon Bruoha Jamal Jafari Isolated ascending aorta dilatation is associated with increased risk of abdominal aortic aneurysm Journal of Cardiothoracic Surgery Abdominal aortic aneurysm Aortic dilatation Screening Computed tomography Transthoracic echocardiography |
| title | Isolated ascending aorta dilatation is associated with increased risk of abdominal aortic aneurysm |
| title_full | Isolated ascending aorta dilatation is associated with increased risk of abdominal aortic aneurysm |
| title_fullStr | Isolated ascending aorta dilatation is associated with increased risk of abdominal aortic aneurysm |
| title_full_unstemmed | Isolated ascending aorta dilatation is associated with increased risk of abdominal aortic aneurysm |
| title_short | Isolated ascending aorta dilatation is associated with increased risk of abdominal aortic aneurysm |
| title_sort | isolated ascending aorta dilatation is associated with increased risk of abdominal aortic aneurysm |
| topic | Abdominal aortic aneurysm Aortic dilatation Screening Computed tomography Transthoracic echocardiography |
| url | https://doi.org/10.1186/s13019-021-01488-w |
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