CCR4 Controls the Suppressive Effects of Regulatory T Cells on Early and Late Events during Severe Sepsis.

CCR4 Controls the Suppressive Effects of Regulatory T Cells on Early and Late Events during Severe Sepsis.

Sepsis is a deadly disease characterized by an overwhelming release of inflammatory mediators and the activation of different types of cells. This altered state of cell activation, termed leukocyte reprogramming, contributes to patient outcome. However, the understanding of the process underlying se...

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Bibliographic Details
Main Authors: Raphael Molinaro, Cyntia Pecli, Rafael F Guilherme, José Carlos Alves-Filho, Fernando Q Cunha, Claudio Canetti, Steven L Kunkel, Marcelo T Bozza, Claudia F Benjamim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4511514?pdf=render

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