The stem cell quiescence and niche signaling is disturbed in the hair follicle of the hairpoor mouse, an MUHH model mouse

The stem cell quiescence and niche signaling is disturbed in the hair follicle of the hairpoor mouse, an MUHH model mouse

Abstract Background Hair follicle stem cells (HFSC) play an essential role in the maintenance of hair homeostasis; during the hair cycle, HFSC remain quiescent for most of its duration. The hairpoor mouse (+ /Hr Hp ), an animal model of Marie-Unna hypotrichosis (MUHH), overexpresses hairless in the...

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Bibliographic Details
Main Authors: Keonwoo Choi, Sang-Hee Park, Seo-Yeon Park, Sungjoo Kim Yoon
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Stem Cell Research & Therapy
Subjects:
Hairpoor mouse
MUHH
Hair follicle stem cell
Wnt signaling
Alopecia
Online Access:https://doi.org/10.1186/s13287-022-02898-w

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