A Mouse Model of Dilated Cardiomyopathy Produced by Isoproterenol Acute Exposure Followed by 5-Fluorouracil Administration

A Mouse Model of Dilated Cardiomyopathy Produced by Isoproterenol Acute Exposure Followed by 5-Fluorouracil Administration

Appropriate dilated cardiomyopathy (DCM) animal models are highly desirable considering the pathophysiological and clinical heterogeneity of DCM. Genetically modified mice are the most widely and intensively utilized research animals for DCM. However, to translate discoveries from basic science into...

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Bibliographic Details
Main Authors: Nadia Salerno, Mariangela Scalise, Fabiola Marino, Andrea Filardo, Antonio Chiefalo, Giuseppe Panuccio, Michele Torella, Antonella De Angelis, Salvatore De Rosa, Georgina M. Ellison-Hughes, Konrad Urbanek, Giuseppe Viglietto, Daniele Torella, Eleonora Cianflone
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
dilated cardiomyopathy
cardiac fibrosis
cardiac inflammation
cardiac senescence
Online Access:https://www.mdpi.com/2308-3425/10/6/225

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