Adenoid cystic carcinoma of the palate and tongue: Report of two cases

Adenoid cystic carcinoma is a rare cancer that arises in major and minor salivary glands with an affinity for nerve invasion. The most common malignancies associated with head and neck and perineural spread are tumors of the minor salivary glands, mucosal and cutaneous origin. However, it is the com...

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Main Authors: Sumanta Kumar Kolay, Raman Kant Sinha, Narendra Nath Singh, Rajkumar Parwani
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-01-01
Series:SRM Journal of Research in Dental Sciences
Subjects:
Online Access:http://www.srmjrds.in/article.asp?issn=0976-433X;year=2014;volume=5;issue=3;spage=195;epage=198;aulast=Kolay
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author Sumanta Kumar Kolay
Raman Kant Sinha
Narendra Nath Singh
Rajkumar Parwani
author_facet Sumanta Kumar Kolay
Raman Kant Sinha
Narendra Nath Singh
Rajkumar Parwani
author_sort Sumanta Kumar Kolay
collection DOAJ
description Adenoid cystic carcinoma is a rare cancer that arises in major and minor salivary glands with an affinity for nerve invasion. The most common malignancies associated with head and neck and perineural spread are tumors of the minor salivary glands, mucosal and cutaneous origin. However, it is the commonest malignant tumor salivary glands, the palate being the commonest site. A 45-years old female patient reported with an asymptomatic growth over left lateral border of the tongue; since last three months. Computed tomography scan revealed the nature of the growth was malignant. An incisional biopsy was performed. Another 45-years old female patient reported with complaints of pain and swelling over palate since last one month. Clinical examination revealed a large multi-lobulated growth over left side of palate. Provisional diagnosis as a salivary gland neoplasm was given. An incisional biopsy was performed. Histological examination confirmed the diagnosis as adenoid cystic carcinoma of tongue as well as of palate for case one and two respectively and both the case were referred to surgical excision of tumors and advised for periodic follow up. Adenoid cystic carcinoma is a slowly growing but highly invasive cancer with high recurrence rate. Lymphatic spread to local lymph nodes is rare. Pleomorphic adenoma with cribriform pattern and polymorphous low grade adenocarcinoma should be considered in the differential diagnosis since they present similarities in the histological pattern. Surgery is the cornerstone of treatment, and its extension depends primarily on the size of the tumor.
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spelling doaj.art-f1b09c57c0614e139e0972de1c2db3342022-12-22T03:02:11ZengWolters Kluwer Medknow PublicationsSRM Journal of Research in Dental Sciences2772-52432772-52512014-01-015319519810.4103/0976-433X.138756Adenoid cystic carcinoma of the palate and tongue: Report of two casesSumanta Kumar KolayRaman Kant SinhaNarendra Nath SinghRajkumar ParwaniAdenoid cystic carcinoma is a rare cancer that arises in major and minor salivary glands with an affinity for nerve invasion. The most common malignancies associated with head and neck and perineural spread are tumors of the minor salivary glands, mucosal and cutaneous origin. However, it is the commonest malignant tumor salivary glands, the palate being the commonest site. A 45-years old female patient reported with an asymptomatic growth over left lateral border of the tongue; since last three months. Computed tomography scan revealed the nature of the growth was malignant. An incisional biopsy was performed. Another 45-years old female patient reported with complaints of pain and swelling over palate since last one month. Clinical examination revealed a large multi-lobulated growth over left side of palate. Provisional diagnosis as a salivary gland neoplasm was given. An incisional biopsy was performed. Histological examination confirmed the diagnosis as adenoid cystic carcinoma of tongue as well as of palate for case one and two respectively and both the case were referred to surgical excision of tumors and advised for periodic follow up. Adenoid cystic carcinoma is a slowly growing but highly invasive cancer with high recurrence rate. Lymphatic spread to local lymph nodes is rare. Pleomorphic adenoma with cribriform pattern and polymorphous low grade adenocarcinoma should be considered in the differential diagnosis since they present similarities in the histological pattern. Surgery is the cornerstone of treatment, and its extension depends primarily on the size of the tumor.http://www.srmjrds.in/article.asp?issn=0976-433X;year=2014;volume=5;issue=3;spage=195;epage=198;aulast=Kolayadenoid cystic carcinomaperineural spreadsalivary glands
spellingShingle Sumanta Kumar Kolay
Raman Kant Sinha
Narendra Nath Singh
Rajkumar Parwani
Adenoid cystic carcinoma of the palate and tongue: Report of two cases
SRM Journal of Research in Dental Sciences
adenoid cystic carcinoma
perineural spread
salivary glands
title Adenoid cystic carcinoma of the palate and tongue: Report of two cases
title_full Adenoid cystic carcinoma of the palate and tongue: Report of two cases
title_fullStr Adenoid cystic carcinoma of the palate and tongue: Report of two cases
title_full_unstemmed Adenoid cystic carcinoma of the palate and tongue: Report of two cases
title_short Adenoid cystic carcinoma of the palate and tongue: Report of two cases
title_sort adenoid cystic carcinoma of the palate and tongue report of two cases
topic adenoid cystic carcinoma
perineural spread
salivary glands
url http://www.srmjrds.in/article.asp?issn=0976-433X;year=2014;volume=5;issue=3;spage=195;epage=198;aulast=Kolay
work_keys_str_mv AT sumantakumarkolay adenoidcysticcarcinomaofthepalateandtonguereportoftwocases
AT ramankantsinha adenoidcysticcarcinomaofthepalateandtonguereportoftwocases
AT narendranathsingh adenoidcysticcarcinomaofthepalateandtonguereportoftwocases
AT rajkumarparwani adenoidcysticcarcinomaofthepalateandtonguereportoftwocases