Tumor-Selective Response to Antibody-Mediated Targeting of αvβ3 Integrin in Ovarian Cancer

Tumor-Selective Response to Antibody-Mediated Targeting of αvβ3 Integrin in Ovarian Cancer

The αvβ3 integrin is expressed on proliferating endothelial cells and some cancer cells, but its expression on ovarian cancer cells and its potential as a therapeutic target are unknown. In this study, expression of the αvβ3 integrin on ovarian cancer cell lines and murine endothelial cells was test...

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Bibliographic Details
Main Authors: Charles N. Landen, Tae-Jin Kim, Yvonne G. Lin, William M. Merritt, Aparna A. Kamat, Liz Y. Han, Whitney A. Spannuth, Alpa M. Nick, Nicholas B. Jennnings, Michael S. Kinch, David Tice, Anil K. Sood
Format: Article
Language:English
Published: Elsevier 2008-11-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558608800231

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