Magnetic Microfluidic Linear Halbach Array Configuration for Cell Separation
The different type of blood entities like red blood cells (RBCs), white blood cell (WBCs) and platelets counts is a critical point in routine medical tests. Circulating tumor cells (CTCs) counting and analysing in the blood is indicative of the stage and origin of cancer in particular time. Here we...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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EDP Sciences
2018-01-01
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| Series: | MATEC Web of Conferences |
| Online Access: | https://doi.org/10.1051/matecconf/201815306008 |
| _version_ | 1829464032410599424 |
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| author | Saeed Omer Duru Iucienne Yulin Deng |
| author_facet | Saeed Omer Duru Iucienne Yulin Deng |
| author_sort | Saeed Omer |
| collection | DOAJ |
| description | The different type of blood entities like red blood cells (RBCs), white blood cell (WBCs) and platelets counts is a critical point in routine medical tests. Circulating tumor cells (CTCs) counting and analysing in the blood is indicative of the stage and origin of cancer in particular time. Here we are describing a proposed microfluidic device, used a magnetic means for CTCs separation from a blood or buffer sample. The device characterizations were simulated using COMSOL MULTIPHYSICS software as well as practically validated. Using a known spiked number of CTCs in the sample, the purity and recovery rate were calculated to be 93% and respectively. |
| first_indexed | 2024-12-13T13:40:55Z |
| format | Article |
| id | doaj.art-f1b1a5d666284ae08c33a5a4304384e3 |
| institution | Directory Open Access Journal |
| issn | 2261-236X |
| language | English |
| last_indexed | 2024-12-13T13:40:55Z |
| publishDate | 2018-01-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | MATEC Web of Conferences |
| spelling | doaj.art-f1b1a5d666284ae08c33a5a4304384e32022-12-21T23:43:35ZengEDP SciencesMATEC Web of Conferences2261-236X2018-01-011530600810.1051/matecconf/201815306008matecconf_icmme2018_06008Magnetic Microfluidic Linear Halbach Array Configuration for Cell SeparationSaeed OmerDuru IucienneYulin DengThe different type of blood entities like red blood cells (RBCs), white blood cell (WBCs) and platelets counts is a critical point in routine medical tests. Circulating tumor cells (CTCs) counting and analysing in the blood is indicative of the stage and origin of cancer in particular time. Here we are describing a proposed microfluidic device, used a magnetic means for CTCs separation from a blood or buffer sample. The device characterizations were simulated using COMSOL MULTIPHYSICS software as well as practically validated. Using a known spiked number of CTCs in the sample, the purity and recovery rate were calculated to be 93% and respectively.https://doi.org/10.1051/matecconf/201815306008 |
| spellingShingle | Saeed Omer Duru Iucienne Yulin Deng Magnetic Microfluidic Linear Halbach Array Configuration for Cell Separation MATEC Web of Conferences |
| title | Magnetic Microfluidic Linear Halbach Array Configuration for Cell Separation |
| title_full | Magnetic Microfluidic Linear Halbach Array Configuration for Cell Separation |
| title_fullStr | Magnetic Microfluidic Linear Halbach Array Configuration for Cell Separation |
| title_full_unstemmed | Magnetic Microfluidic Linear Halbach Array Configuration for Cell Separation |
| title_short | Magnetic Microfluidic Linear Halbach Array Configuration for Cell Separation |
| title_sort | magnetic microfluidic linear halbach array configuration for cell separation |
| url | https://doi.org/10.1051/matecconf/201815306008 |
| work_keys_str_mv | AT saeedomer magneticmicrofluidiclinearhalbacharrayconfigurationforcellseparation AT duruiucienne magneticmicrofluidiclinearhalbacharrayconfigurationforcellseparation AT yulindeng magneticmicrofluidiclinearhalbacharrayconfigurationforcellseparation |