Striae gravidarum and different modalities of therapy: a review and update

The term striae gravidarum (SG) refers to a kind of striae distensae (SD) that develops particularly during pregnancy. According to the level of maturity of the lesions, SG is divided into striae rubra (SR) and striae alba (SA). The pathogenesis remains unclear; recent studies have implicated abnorm...

Full description

Bibliographic Details
Main Authors: Yangyiyi Yu, Haijing Wu, Heng Yin, Qianjin Lu
Format: Article
Language:English
Published: Taylor & Francis Group 2022-04-01
Series:Journal of Dermatological Treatment
Subjects:
Online Access:http://dx.doi.org/10.1080/09546634.2020.1825614
_version_ 1797683580587999232
author Yangyiyi Yu
Haijing Wu
Heng Yin
Qianjin Lu
author_facet Yangyiyi Yu
Haijing Wu
Heng Yin
Qianjin Lu
author_sort Yangyiyi Yu
collection DOAJ
description The term striae gravidarum (SG) refers to a kind of striae distensae (SD) that develops particularly during pregnancy. According to the level of maturity of the lesions, SG is divided into striae rubra (SR) and striae alba (SA). The pathogenesis remains unclear; recent studies have implicated abnormalities in elastic fibers, collagen fibrils, and other extracellular matrix (ECM) components. Changes in the expression of hormone receptors and hormone levels have also been hypothesized. Considering this new information, we reviewed successful treatments of SG and listed them in two tables. Our review found that topical treatments were relatively weak compared with laser and light treatment, with which the appearance of SR and SA can be significantly improved. Lasers combined with other modalities, such as additional energy devices and topical agents, were also proven effective, but more large-scale trials are necessary.
first_indexed 2024-03-12T00:16:29Z
format Article
id doaj.art-f1b298d114d24f1e8a4399053589c31e
institution Directory Open Access Journal
issn 0954-6634
1471-1753
language English
last_indexed 2024-03-12T00:16:29Z
publishDate 2022-04-01
publisher Taylor & Francis Group
record_format Article
series Journal of Dermatological Treatment
spelling doaj.art-f1b298d114d24f1e8a4399053589c31e2023-09-15T14:28:49ZengTaylor & Francis GroupJournal of Dermatological Treatment0954-66341471-17532022-04-013331243125110.1080/09546634.2020.18256141825614Striae gravidarum and different modalities of therapy: a review and updateYangyiyi Yu0Haijing Wu1Heng Yin2Qianjin Lu3Department of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical EpigenomicsDepartment of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical EpigenomicsDepartment of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical EpigenomicsDepartment of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical EpigenomicsThe term striae gravidarum (SG) refers to a kind of striae distensae (SD) that develops particularly during pregnancy. According to the level of maturity of the lesions, SG is divided into striae rubra (SR) and striae alba (SA). The pathogenesis remains unclear; recent studies have implicated abnormalities in elastic fibers, collagen fibrils, and other extracellular matrix (ECM) components. Changes in the expression of hormone receptors and hormone levels have also been hypothesized. Considering this new information, we reviewed successful treatments of SG and listed them in two tables. Our review found that topical treatments were relatively weak compared with laser and light treatment, with which the appearance of SR and SA can be significantly improved. Lasers combined with other modalities, such as additional energy devices and topical agents, were also proven effective, but more large-scale trials are necessary.http://dx.doi.org/10.1080/09546634.2020.1825614striae distensaestriae gravidarumlaser therapyphototherapy
spellingShingle Yangyiyi Yu
Haijing Wu
Heng Yin
Qianjin Lu
Striae gravidarum and different modalities of therapy: a review and update
Journal of Dermatological Treatment
striae distensae
striae gravidarum
laser therapy
phototherapy
title Striae gravidarum and different modalities of therapy: a review and update
title_full Striae gravidarum and different modalities of therapy: a review and update
title_fullStr Striae gravidarum and different modalities of therapy: a review and update
title_full_unstemmed Striae gravidarum and different modalities of therapy: a review and update
title_short Striae gravidarum and different modalities of therapy: a review and update
title_sort striae gravidarum and different modalities of therapy a review and update
topic striae distensae
striae gravidarum
laser therapy
phototherapy
url http://dx.doi.org/10.1080/09546634.2020.1825614
work_keys_str_mv AT yangyiyiyu striaegravidarumanddifferentmodalitiesoftherapyareviewandupdate
AT haijingwu striaegravidarumanddifferentmodalitiesoftherapyareviewandupdate
AT hengyin striaegravidarumanddifferentmodalitiesoftherapyareviewandupdate
AT qianjinlu striaegravidarumanddifferentmodalitiesoftherapyareviewandupdate