Roles of organelle-specific autophagy in hepatocytes in the development and treatment of non-alcoholic fatty liver disease
Abstract. Non-alcoholic fatty liver disease (NAFLD) is a disorder of lipid metabolism. The lipotoxic intermediates of lipid metabolism cause mitochondrial dysfunction and endoplasmic reticulum stress. Organelle-specific autophagy is responsible for the removal of dysfunctional organelles to maintain...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Wolters Kluwer
2022-07-01
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Series: | Chinese Medical Journal |
Online Access: | http://journals.lww.com/10.1097/CM9.0000000000002263 |