Roles of organelle-specific autophagy in hepatocytes in the development and treatment of non-alcoholic fatty liver disease

Abstract. Non-alcoholic fatty liver disease (NAFLD) is a disorder of lipid metabolism. The lipotoxic intermediates of lipid metabolism cause mitochondrial dysfunction and endoplasmic reticulum stress. Organelle-specific autophagy is responsible for the removal of dysfunctional organelles to maintain...

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Bibliographic Details
Main Authors: Yizhi Zhang, Yu Chen, Lishao Guo
Format: Article
Language:English
Published: Wolters Kluwer 2022-07-01
Series:Chinese Medical Journal
Online Access:http://journals.lww.com/10.1097/CM9.0000000000002263

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