Astrocytes Protect Neurons in the Hippocampal CA3 Against Ischemia by Suppressing the Intracellular Ca2+ Overload

Astrocytes Protect Neurons in the Hippocampal CA3 Against Ischemia by Suppressing the Intracellular Ca2+ Overload

In the hippocampus, delayed neuronal death is normally seen in neurons of the CA1 region but not in those of the CA3 region. Astrocytes have been reported to play multiple supporting or pathological roles in neuronal functioning. While evidence indicates that astrocytes could exert neuroprotective e...

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Bibliographic Details
Main Authors: Chuanqi Sun, Yasuko Fukushi, Yong Wang, Seiji Yamamoto
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Cellular Neuroscience
Subjects:
astrocyte
brain ischemia
neuroprotection
intracellular Ca2+ overload
delayed neuronal death
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00280/full

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