Neutrophils in the Pathogenesis of Rheumatoid Arthritis and Systemic Lupus Erythematosus: Same Foe Different M.O.

Neutrophils in the Pathogenesis of Rheumatoid Arthritis and Systemic Lupus Erythematosus: Same Foe Different M.O.

Dysregulated neutrophil activation contributes to the pathogenesis of autoimmune diseases including rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Neutrophil-derived reactive oxygen species (ROS) and granule proteases are implicated in damage to and destruction of host tissues in...

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Bibliographic Details
Main Authors: Michele Fresneda Alarcon, Zoe McLaren, Helen Louise Wright
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
neutrophils
rheumatoid arthritis
systemic lupus erythematosus
NETs
low density granulocytes
immunometabolism
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.649693/full

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