Influence of Aqueous Solubility-Enhancing Excipients on the Microstructural Characteristics of Furosemide-Loaded Electrospun Nanofibers

Influence of Aqueous Solubility-Enhancing Excipients on the Microstructural Characteristics of Furosemide-Loaded Electrospun Nanofibers

Electrospun nanofibers were prepared from furosemide-containing hydroxypropyl cellulose and poly(vinylpyrrolidone) aqueous solutions using different solubility enhancers. In one case, a solubilizer, triethanolamine, was applied, while in the other case a pH-modifier, sodium hydroxide, was applied. S...

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Bibliographic Details
Main Authors: Andrea Kovács, Adrienn Kazsoki, Balázs Démuth, Bernadett Szirányi, János Madarász, Károly Süvegh, Romána Zelkó
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Pharmaceutics
Subjects:
electrospinning
nanofiber
furosemide
morphology
physical-chemical characterization
microstructural distinction
Online Access:https://www.mdpi.com/1999-4923/12/4/385

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