Enrichment on steps, not genes, improves inference of differentially expressed pathways.

Enrichment on steps, not genes, improves inference of differentially expressed pathways.

Enrichment analysis is frequently used in combination with differential expression data to investigate potential commonalities amongst lists of genes and generate hypotheses for further experiments. However, current enrichment analysis approaches on pathways ignore the functional relationships betwe...

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Bibliographic Details
Main Authors:	Nicholas Markarian, Kimberly M Van Auken, Dustin Ebert, Paul W Sternberg
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2024-03-01
Series:	PLoS Computational Biology
Online Access:	https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1011968&type=printable

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