The role of circulating tumor DNA in patients with colon cancer
The term “liquid biopsy” describes the study of various tumor derivatives (circulating tumor DNA, circulating tumor cells, tumor RNA, tumor proteins) in the blood plasma. Results of liquid biopsy provide real-time information on the molecular pathologies and morphologicalfeatures throughout the whol...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
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“ABV-press” Publishing house”, LLC
2016-10-01
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| Series: | Тазовая хирургия и онкология |
| Subjects: | |
| Online Access: | https://ok.abvpress.ru/jour/article/view/181 |
| _version_ | 1827880138222600192 |
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| author | M. Yu. Fedyanin E. M. Polyanskaya S. A. Tjulyandin |
| author_facet | M. Yu. Fedyanin E. M. Polyanskaya S. A. Tjulyandin |
| author_sort | M. Yu. Fedyanin |
| collection | DOAJ |
| description | The term “liquid biopsy” describes the study of various tumor derivatives (circulating tumor DNA, circulating tumor cells, tumor RNA, tumor proteins) in the blood plasma. Results of liquid biopsy provide real-time information on the molecular pathologies and morphologicalfeatures throughout the whole tumor mass and allow to estimate evolutionary changes of tumor mass in the dynamics, heterogeneity of mass formation and effectiveness of the therapy. Despite the impressive perspective of this method in the diagnosis, monitoring of disease, there is a number of problems for the implementation of liquid biopsy for various cancer pathologies. In this literature review, we focus on the role of circulating DNA as a source of information about the tumor in patients with colon cancer. |
| first_indexed | 2024-03-12T18:17:45Z |
| format | Article |
| id | doaj.art-f1c1fc088a5d4cb2beee686d3f778359 |
| institution | Directory Open Access Journal |
| issn | 2686-9594 |
| language | Russian |
| last_indexed | 2024-03-12T18:17:45Z |
| publishDate | 2016-10-01 |
| publisher | “ABV-press” Publishing house”, LLC |
| record_format | Article |
| series | Тазовая хирургия и онкология |
| spelling | doaj.art-f1c1fc088a5d4cb2beee686d3f7783592023-08-02T09:03:58Zrus“ABV-press” Publishing house”, LLCТазовая хирургия и онкология2686-95942016-10-0163435210.17650/2220-3478-2016-6-3-43-52156The role of circulating tumor DNA in patients with colon cancerM. Yu. Fedyanin0E. M. Polyanskaya1S. A. Tjulyandin2N. N. Blokhin Russian Cancer Research Center of the Ministry of Health of RussiaN. N. Blokhin Russian Cancer Research Center of the Ministry of Health of RussiaN. N. Blokhin Russian Cancer Research Center of the Ministry of Health of RussiaThe term “liquid biopsy” describes the study of various tumor derivatives (circulating tumor DNA, circulating tumor cells, tumor RNA, tumor proteins) in the blood plasma. Results of liquid biopsy provide real-time information on the molecular pathologies and morphologicalfeatures throughout the whole tumor mass and allow to estimate evolutionary changes of tumor mass in the dynamics, heterogeneity of mass formation and effectiveness of the therapy. Despite the impressive perspective of this method in the diagnosis, monitoring of disease, there is a number of problems for the implementation of liquid biopsy for various cancer pathologies. In this literature review, we focus on the role of circulating DNA as a source of information about the tumor in patients with colon cancer.https://ok.abvpress.ru/jour/article/view/181circulating tumor dnacolon cancerbiomarkers |
| spellingShingle | M. Yu. Fedyanin E. M. Polyanskaya S. A. Tjulyandin The role of circulating tumor DNA in patients with colon cancer Тазовая хирургия и онкология circulating tumor dna colon cancer biomarkers |
| title | The role of circulating tumor DNA in patients with colon cancer |
| title_full | The role of circulating tumor DNA in patients with colon cancer |
| title_fullStr | The role of circulating tumor DNA in patients with colon cancer |
| title_full_unstemmed | The role of circulating tumor DNA in patients with colon cancer |
| title_short | The role of circulating tumor DNA in patients with colon cancer |
| title_sort | role of circulating tumor dna in patients with colon cancer |
| topic | circulating tumor dna colon cancer biomarkers |
| url | https://ok.abvpress.ru/jour/article/view/181 |
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