Interaction of Hydroxychloroquine with Pharmacokinetically Important Drug Transporters

Interaction of Hydroxychloroquine with Pharmacokinetically Important Drug Transporters

(1) Background: Hydroxychloroquine is used to treat malaria and autoimmune diseases, and its potential use against COVID-19 is currently under investigation. Thus far, information on interactions of hydroxychloroquine with drug transporters mediating drug-drug interactions is limited. We assessed th...

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Bibliographic Details
Main Authors: Johanna Weiss, Gzona Bajraktari-Sylejmani, Walter E. Haefeli
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Pharmaceutics
Subjects:
hydroxychloroquine
drug-drug interaction
drug transporters
inhibition
induction
P-glycoprotein
Online Access:https://www.mdpi.com/1999-4923/12/10/919

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