The role of stromal cancer-associated fibroblasts in pancreatic cancer

The role of stromal cancer-associated fibroblasts in pancreatic cancer

Abstract Pancreatic ductal adenocarcinoma (PDAC) is a lethal cancer generally refractory to conventional treatments. Cancer-associated fibroblasts (CAFs) are cellular components of the desmoplastic stroma characteristic to the tumor that contributes to this treatment resistance. Various markers for...

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Bibliographic Details
Main Authors: Dagny von Ahrens, Tushar D. Bhagat, Deepak Nagrath, Anirban Maitra, Amit Verma
Format: Article
Language:English
Published: BMC 2017-03-01
Series:Journal of Hematology & Oncology
Subjects:
Pancreas
Adenocarcinoma
Stroma
Tumor microenvironment
Cancer-associated fibroblast
Online Access:http://link.springer.com/article/10.1186/s13045-017-0448-5

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