The KEAP1-NRF2 System and Esophageal Cancer

The KEAP1-NRF2 System and Esophageal Cancer

NRF2 (nuclear factor erythroid 2-related factor 2) is a transcription factor that regulates the expression of many cytoprotective genes. NRF2 activation is mainly regulated by KEAP1 (kelch-like ECH-associated protein 1) through ubiquitination and proteasome degradation. Esophageal cancer is classifi...

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Bibliographic Details
Main Authors:	Wataru Hirose, Hiroyuki Oshikiri, Keiko Taguchi, Masayuki Yamamoto
Format:	Article
Language:	English
Published:	MDPI AG 2022-09-01
Series:	Cancers
Subjects:	NRF2 KEAP1 esophagus esophageal cancer ESCC cell competition
Online Access:	https://www.mdpi.com/2072-6694/14/19/4702

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