Autocrine CTHRC1 activates hepatic stellate cells and promotes liver fibrosis by activating TGF-β signalingResearch in context

Autocrine CTHRC1 activates hepatic stellate cells and promotes liver fibrosis by activating TGF-β signalingResearch in context

Background: Hepatic fibrosis is caused by chronic liver injury and may progress toward liver cirrhosis, and even hepatocellular carcinoma. However, current treatment is not satisfactory. Therefore, there is a mandate to find novel therapeutic targets to improve therapy, and biomarkers to monitor the...

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Bibliographic Details
Main Authors: Jun Li, Yahui Wang, Mingze Ma, Shuheng Jiang, Xueli Zhang, Yanli Zhang, Xiaomei Yang, Chunjie Xu, Guangang Tian, Qing Li, Yang Wang, Lei Zhu, Huizhen Nie, Mingxuan Feng, Qiang Xia, Jianren Gu, Qing Xu, Zhigang Zhang
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S235239641930009X

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http://www.sciencedirect.com/science/article/pii/S235239641930009X

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