SIRGs score may be a predictor of prognosis and immunotherapy response for esophagogastric junction adenocarcinoma

SIRGs score may be a predictor of prognosis and immunotherapy response for esophagogastric junction adenocarcinoma

BackgroundEsophagogastric junction adenocarcinoma (EGJA) is a special malignant tumor with unknown biological behavior. PD-1 checkpoint inhibitors have been recommended as first-line treatment for advanced EGJA patients. However, the biomarkers for predicting immunotherapy response remain controvers...

Full description

Bibliographic Details
Main Authors:	Li-Ying OuYang, Zi-Jian Deng, Yu-Feng You, Jia-Ming Fang, Xi-Jie Chen, Jun-Jie Liu, Xian-Zhe Li, Lei Lian, Shi Chen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-08-01
Series:	Frontiers in Immunology
Subjects:	esophagogastric junction adenocarcinoma SIRGs score prognosis immunotherapy tumor microenvironment
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.977894/full

Similar Items

Bioinformatic analysis of adenocarcinoma at esophagogastric junction and mutation sites screening of Involucrin gene
by: LYU Xue, LI Xue-wei, YANG Ting, ZHENG Jin-xiu, ZHU Zi-he, YANG Tao, XU Jun
Published: (2022-02-01)

Prognostic significance of NFIA and NFIB in esophageal squamous carcinoma and esophagogastric junction adenocarcinoma
by: Bo Yang, et al.
Published: (2018-05-01)

Analysis of N6-Methyladenosine Methylome in Adenocarcinoma of Esophagogastric Junction
by: Jia-Bin Huang, et al.
Published: (2022-01-01)

Cervical metastasis of esophagogastric junction cancer
by: Zhiqiang Cai, et al.
Published: (2012-01-01)

Safety, efficacy, and selection strategy of laparoscopic local gastrectomy for gastrointestinal stromal tumors in the esophagogastric junction
by: Haiqiao Zhang, et al.
Published: (2022-09-01)

Patterns of recurrence in adenocarcinoma of the esophagogastric junction: a retrospective study
by: Haitao Xu, et al.
Published: (2020-06-01)

Acute Anisakiasis at the Esophagogastric Junction Mimicking Angina Pectoris
by: Dong Chan Joo, et al.
Published: (2021-06-01)

Relationship between the number of dissected lymph node and the pathological staging in esophagogastric junction adenocarcinoma
by: Renwang Hu, et al.
Published: (2023-12-01)

Mixed adenoneuroendocrine carcinoma of the esophagogastric junction: a case report
by: Miho Yamamoto, et al.
Published: (2018-06-01)

Gross tumor volume of adenocarcinoma of esophagogastric junction corresponding to cT and cN stages measured with computed tomography to quantitatively determine resectabiliy: A case control study
by: Ke-ying Li, et al.
Published: (2022-11-01)

Prognostic impact of sarcopenia in patients with locally advanced adenocarcinoma of the esophagogastric junction treated with neoadjuvant chemoradiotherapy
by: Jiao Ming, et al.
Published: (2023-01-01)

Diagnostic performance in T staging for patients with esophagogastric junction cancer using high-resolution MRI: a comparison with conventional MRI at 3 tesla
by: Yuan Yuan, et al.
Published: (2019-12-01)

Accuracy of Preoperative Endoscopy in Determining Tumor Location Required for Surgical Planning for Esophagogastric Junction Cancer
by: Koichi Okumura, et al.
Published: (2021-07-01)

“Sandwich Therapy”—Immunotherapy Plus Concurrent Chemoradiotherapy for Advanced Esophagogastric Junction Carcinoma: Report of Two Cases and Literature Review
by: Lei Wu, et al.
Published: (2022-05-01)

How to decide surgical procedure for esophagogastric junction cancer?
by: Yasuyuki Seto, et al.
Published: (2020-02-01)

A case report of adenosquamous carcinoma of the esophagogastric junction
by: Harunari Fukai, et al.
Published: (2022-05-01)

Effect of Radical Surgery for Advanced Adenocarcinoma of Esophagogastric Junction on Perioperative Cellular Cell Immunity
by: Shou-miao Li, et al.
Published: (2021-02-01)

The Value of Predicting Human Epidermal Growth Factor Receptor 2 Status in Adenocarcinoma of the Esophagogastric Junction on CT-Based Radiomics Nomogram
by: Shuxing Wang, et al.
Published: (2021-10-01)

Endoscopic resection of giant gastrointestinal stromal tumor at the esophagogastric junction: a case report
by: Feng Xue, et al.
Published: (2019-12-01)

Enhanced CT-based radiomics predicts pathological complete response after neoadjuvant chemotherapy for advanced adenocarcinoma of the esophagogastric junction: a two-center study
by: Wenpeng Huang, et al.
Published: (2022-08-01)

Recommendations for the treatment of patients with esophageal cancer and esophagogastric junction
by: Erik Brecelj, et al.
Published: (2022-11-01)

Total neoadjuvant therapy for locally advanced gastric cancer and esophagogastric junction adenocarcinoma: study protocol for a prospective, multicenter, single-arm, phase II clinical trial
by: Jinming Shi, et al.
Published: (2022-07-01)

Development and validation of a survival nomogram for patients with Siewert type II/III adenocarcinoma of the esophagogastric junction based on real-world data
by: Jian Chen, et al.
Published: (2021-05-01)

Endoscopic Versus Surgical Therapy for Early Esophagogastric Junction Adenocarcinoma Based on Lymph Node Metastasis Risk: A Population-Based Analysis
by: Hua Ye, et al.
Published: (2021-12-01)

Expression of Programmed Cell Death 1 and Lymphocyte Activation Gene 3 in Perioperation of Adenocarcinoma of Esophagogastric Junction and Related Significance
by: ZHANG Wei, et al.
Published: (2019-05-01)

Clinicopathological Characteristics and Survival Predictions for Adenocarcinoma of the Esophagogastric Junction: A SEER Population-Based Retrospective Study
by: Liu X, et al.
Published: (2021-12-01)

Hub genes in adenocarcinoma of the esophagogastric junction based on weighted gene co-expression network analysis and immunohistochemistry
by: Zhiyong Lai, et al.
Published: (2023-11-01)

Long-term outcomes and prognostic factor analysis of resected Siewert type II adenocarcinoma of esophagogastric junction in China: a seven-year study
by: Yiding Feng, et al.
Published: (2020-11-01)

Immune Infiltration Subtypes Characterization and Identification of Prognosis-Related lncRNAs in Adenocarcinoma of the Esophagogastric Junction
by: Xin Hu, et al.
Published: (2021-05-01)

Expression analysis of the TGF-β/SMAD target genes in adenocarcinoma of esophagogastric junction
by: Peng Defeng, et al.
Published: (2016-01-01)

Serum insulin-like growth factor binding protein 3 as a promising diagnostic and prognostic biomarker in esophagogastric junction adenocarcinoma
by: Tian-Yan Ding, et al.
Published: (2022-11-01)

Lack of EGFR mutations benefiting gefitinib treatment in adenocarcinoma of esophagogastric junction
by: Wang Wen-Ping, et al.
Published: (2012-01-01)

Platelet Count/Spleen Thickness Ratio and the Risk of Variceal Bleeding in Cirrhosis With Esophagogastric Varices
by: Huimin Liu, et al.
Published: (2022-07-01)

Minimum number of necessary lymph nodes for the accurate staging of adenocarcinoma of esophagogastric junction
by: Jiabin Zheng, et al.
Published: (2023-03-01)

Neoadjuvant chemoradiotherapy improves survival in locally advanced adenocarcinoma of esophagogastric junction compared with neoadjuvant chemotherapy: a propensity score matching analysis
by: Jing Li, et al.
Published: (2021-03-01)

miRNA-146a rs2910164 C>G polymorphism increased the risk of esophagogastric junction adenocarcinoma: a case–control study involving 2,740 participants
by: Chen Y, et al.
Published: (2018-06-01)

Lymphovascular Invasion as a Prognostic Factor in Non-Metastatic Adenocarcinoma of Esophagogastric Junction After Radical Surgery
by: Zheng C, et al.
Published: (2020-12-01)

HN1L promotes invasion and metastasis of the esophagogastric junction adenocarcinoma
by: Zhao Yang Wang, et al.
Published: (2021-03-01)

Adenocarcinosarcoma at the esophagogastric junction with long esophageal invasion: a case report
by: Kenichiro Furukawa, et al.
Published: (2020-01-01)

Effect of operation-introducing hyperthermic intraperitoneal chemotherapy on cellular immune function in patients with adenocarcinoma of the esophagogastric junction
by: Zhiyong Nie, et al.
Published: (2022-01-01)