Meloxicam Targets COX-2/NOX1/NOX4/Nrf2 Axis to Ameliorate the Depression-like Neuropathology Induced by Chronic Restraint Stress in Rats

Meloxicam has shown significant neuroprotection in experimental models of stroke, Alzheimer’s disease, and Parkinson’s disease. However, the potential of meloxicam to treat depression-like neuropathology in a chronic restraint stress (CRS) model and the associated molecular changes has been insuffic...

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Main Authors: Hany H. Arab, Ali Khames, Mostafa K. Mohammad, Shuruq E. Alsufyani, Ahmed M. Ashour, Azza A. K. El-Sheikh, Hany W. Darwish, Amany M. Gad
פורמט: Article
שפה:English
יצא לאור: MDPI AG 2023-06-01
סדרה:Pharmaceuticals
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גישה מקוונת:https://www.mdpi.com/1424-8247/16/6/848