HIV-1 DNA predicts disease progression and post-treatment virological control

HIV-1 DNA predicts disease progression and post-treatment virological control

In HIV-1 infection, a population of latently infected cells facilitates viral persistence despite antiretroviral therapy (ART). With the aim of identifying individuals in whom ART might induce a period of viraemic control on stopping therapy, we hypothesised that quantification of the pool of latent...

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Bibliographic Details
Main Authors: James P Williams, Jacob Hurst, Wolfgang Stöhr, Nicola Robinson, Helen Brown, Martin Fisher, Sabine Kinloch, David Cooper, Mauro Schechter, Giuseppe Tambussi, Sarah Fidler, Mary Carrington, Abdel Babiker, Jonathan Weber, Kersten K Koelsch, Anthony D Kelleher, Rodney E Phillips, John Frater, on behalf of the SPARTAC trial investigators
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-09-01
Series:eLife
Subjects:
HIV-1
reservoir
antiretroviral therapy
cure
primary infection
Online Access:https://elifesciences.org/articles/03821

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