Elagolix in the treatment of endometriosis: impact beyond pain symptoms
While the most common symptom associated with endometriosis is pelvic pain, the systemic manifestations of the disease and the accompanying adverse psychological, emotional, social, familial, sexual, educational and workplace effects are increasingly recognized. Elagolix is an oral gonadotropin-rele...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2020-11-01
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| Series: | Therapeutic Advances in Reproductive Health |
| Online Access: | https://doi.org/10.1177/2633494120964517 |
| _version_ | 1819052310222864384 |
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| author | David F. Archer Ahmed M. Soliman Sanjay K. Agarwal Hugh S. Taylor |
| author_facet | David F. Archer Ahmed M. Soliman Sanjay K. Agarwal Hugh S. Taylor |
| author_sort | David F. Archer |
| collection | DOAJ |
| description | While the most common symptom associated with endometriosis is pelvic pain, the systemic manifestations of the disease and the accompanying adverse psychological, emotional, social, familial, sexual, educational and workplace effects are increasingly recognized. Elagolix is an oral gonadotropin-releasing hormone receptor antagonist that is approved for the management of moderate to severe pain associated with endometriosis. However, the benefits of elagolix extend beyond reducing pain symptoms. This article reviews the non-pain systemic manifestations associated with endometriosis and summarizes the beneficial effects of elagolix on non-pain outcomes. This includes improvements in quality of life, reductions in fatigue and improvements in workplace and household productivity. These results indicate that elagolix provides non-pain benefits in women with endometriosis and improves outcomes that are clinically meaningful to patients. |
| first_indexed | 2024-12-21T12:17:48Z |
| format | Article |
| id | doaj.art-f1d50ede81344d98a88a55453a50e685 |
| institution | Directory Open Access Journal |
| issn | 2633-4941 |
| language | English |
| last_indexed | 2024-12-21T12:17:48Z |
| publishDate | 2020-11-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Therapeutic Advances in Reproductive Health |
| spelling | doaj.art-f1d50ede81344d98a88a55453a50e6852022-12-21T19:04:24ZengSAGE PublishingTherapeutic Advances in Reproductive Health2633-49412020-11-011410.1177/2633494120964517Elagolix in the treatment of endometriosis: impact beyond pain symptomsDavid F. ArcherAhmed M. SolimanSanjay K. AgarwalHugh S. TaylorWhile the most common symptom associated with endometriosis is pelvic pain, the systemic manifestations of the disease and the accompanying adverse psychological, emotional, social, familial, sexual, educational and workplace effects are increasingly recognized. Elagolix is an oral gonadotropin-releasing hormone receptor antagonist that is approved for the management of moderate to severe pain associated with endometriosis. However, the benefits of elagolix extend beyond reducing pain symptoms. This article reviews the non-pain systemic manifestations associated with endometriosis and summarizes the beneficial effects of elagolix on non-pain outcomes. This includes improvements in quality of life, reductions in fatigue and improvements in workplace and household productivity. These results indicate that elagolix provides non-pain benefits in women with endometriosis and improves outcomes that are clinically meaningful to patients.https://doi.org/10.1177/2633494120964517 |
| spellingShingle | David F. Archer Ahmed M. Soliman Sanjay K. Agarwal Hugh S. Taylor Elagolix in the treatment of endometriosis: impact beyond pain symptoms Therapeutic Advances in Reproductive Health |
| title | Elagolix in the treatment of endometriosis: impact beyond pain symptoms |
| title_full | Elagolix in the treatment of endometriosis: impact beyond pain symptoms |
| title_fullStr | Elagolix in the treatment of endometriosis: impact beyond pain symptoms |
| title_full_unstemmed | Elagolix in the treatment of endometriosis: impact beyond pain symptoms |
| title_short | Elagolix in the treatment of endometriosis: impact beyond pain symptoms |
| title_sort | elagolix in the treatment of endometriosis impact beyond pain symptoms |
| url | https://doi.org/10.1177/2633494120964517 |
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