MicroRNA199a-Based Post-transcriptional Detargeting of Gene Vectors for Hepatocellular Carcinoma
A gene therapeutic platform needs to be both efficient and safe. The criterion of safety is particularly important for diseases like hepatocellular carcinoma (HCC), which develop in a background of an already compromised liver. Gene vectors can be constructed either by targeting HCC or by detargetin...
Main Authors: | Bijay Dhungel, Charmaine A. Ramlogan-Steel, Christopher J. Layton, Jason C. Steel |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-12-01
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Series: | Molecular Therapy: Nucleic Acids |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2162253118302312 |
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