Restless Legs Syndrome: From Diagnosis to Treatment
Restless legs syndrome (RLS) can be described by an urge to move limbs that typically coincides with an uncomfortable sensation. When at rest or inactivity, signs may start or develop worse; they usually go away when one moves or gets up for a walk. RLS can be both idiopathic or secondary to many ki...
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| Format: | Article |
| Language: | English |
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Duzce University
2023-12-01
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| Series: | Düzce Tıp Fakültesi Dergisi |
| Subjects: | |
| Online Access: | https://dergipark.org.tr/en/download/article-file/3540170 |
| _version_ | 1797376458405969920 |
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| author | Yıldız Değirmenci Rashad İsmayılov |
| author_facet | Yıldız Değirmenci Rashad İsmayılov |
| author_sort | Yıldız Değirmenci |
| collection | DOAJ |
| description | Restless legs syndrome (RLS) can be described by an urge to move limbs that typically coincides with an uncomfortable sensation. When at rest or inactivity, signs may start or develop worse; they usually go away when one moves or gets up for a walk. RLS can be both idiopathic or secondary to many kinds of health conditions, such as deficiency of iron, diabetes, obesity, hypothyroidism, and chronic renal failure. At the admission, secondary causes and iron tests, such as transferrin saturation and ferritin, must be evaluated. Assessments should be repeated when symptoms worsen, or when augmentation develops. Augmentation is a significant adverse effect of therapy by levodopa and dopamine agonists. More severe signs, early appearance of symptoms, and spreading of symptoms from the legs to other body parts are indicative of augmentation. Non-pharmacological treatments help some RLS patients control their symptoms. Iron-replacement therapy is a first-line treatment option for patients with indications of low body iron stores. The use of α2δ ligands as initial treatments instead of dopamine agonists has been recommended recently. |
| first_indexed | 2024-03-08T19:38:57Z |
| format | Article |
| id | doaj.art-f1db0ed278324b3689a3517d7eb33b15 |
| institution | Directory Open Access Journal |
| issn | 1307-671X |
| language | English |
| last_indexed | 2024-03-08T19:38:57Z |
| publishDate | 2023-12-01 |
| publisher | Duzce University |
| record_format | Article |
| series | Düzce Tıp Fakültesi Dergisi |
| spelling | doaj.art-f1db0ed278324b3689a3517d7eb33b152023-12-25T14:41:52ZengDuzce UniversityDüzce Tıp Fakültesi Dergisi1307-671X2023-12-0125321221710.18678/dtfd.139145097Restless Legs Syndrome: From Diagnosis to TreatmentYıldız Değirmenci0Rashad İsmayılov1İSTANBUL SAĞLIK VE TEKNOLOJİ ÜNİVERSİTESİ, TIP FAKÜLTESİİSTANBUL SAĞLIK VE TEKNOLOJİ ÜNİVERSİTESİ, TIP FAKÜLTESİRestless legs syndrome (RLS) can be described by an urge to move limbs that typically coincides with an uncomfortable sensation. When at rest or inactivity, signs may start or develop worse; they usually go away when one moves or gets up for a walk. RLS can be both idiopathic or secondary to many kinds of health conditions, such as deficiency of iron, diabetes, obesity, hypothyroidism, and chronic renal failure. At the admission, secondary causes and iron tests, such as transferrin saturation and ferritin, must be evaluated. Assessments should be repeated when symptoms worsen, or when augmentation develops. Augmentation is a significant adverse effect of therapy by levodopa and dopamine agonists. More severe signs, early appearance of symptoms, and spreading of symptoms from the legs to other body parts are indicative of augmentation. Non-pharmacological treatments help some RLS patients control their symptoms. Iron-replacement therapy is a first-line treatment option for patients with indications of low body iron stores. The use of α2δ ligands as initial treatments instead of dopamine agonists has been recommended recently.https://dergipark.org.tr/en/download/article-file/3540170restless legs syndromeaugmentationiron deficiencyiron therapyhuzursuz bacaklar sendromuaugmentasyondemir eksikliğidemir tedavisi |
| spellingShingle | Yıldız Değirmenci Rashad İsmayılov Restless Legs Syndrome: From Diagnosis to Treatment Düzce Tıp Fakültesi Dergisi restless legs syndrome augmentation iron deficiency iron therapy huzursuz bacaklar sendromu augmentasyon demir eksikliği demir tedavisi |
| title | Restless Legs Syndrome: From Diagnosis to Treatment |
| title_full | Restless Legs Syndrome: From Diagnosis to Treatment |
| title_fullStr | Restless Legs Syndrome: From Diagnosis to Treatment |
| title_full_unstemmed | Restless Legs Syndrome: From Diagnosis to Treatment |
| title_short | Restless Legs Syndrome: From Diagnosis to Treatment |
| title_sort | restless legs syndrome from diagnosis to treatment |
| topic | restless legs syndrome augmentation iron deficiency iron therapy huzursuz bacaklar sendromu augmentasyon demir eksikliği demir tedavisi |
| url | https://dergipark.org.tr/en/download/article-file/3540170 |
| work_keys_str_mv | AT yıldızdegirmenci restlesslegssyndromefromdiagnosistotreatment AT rashadismayılov restlesslegssyndromefromdiagnosistotreatment |