Gender Bias in Human Systemic Lupus Erythematosus: A Problem of Steroid Receptor Action?

Gender Bias in Human Systemic Lupus Erythematosus: A Problem of Steroid Receptor Action?

Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune disease resulting from abnormal interactions between T and B cells. The acquisition of SLE is linked to genetic susceptibility, and diverse environmental agents can trigger disease onset in genetically susceptible individuals. Howev...

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Bibliographic Details
Main Authors: Virginia Rider, Nabih I. Abdou, Bruce F. Kimler, Nanyan Lu, Susan Brown, Brooke L. Fridley
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Immunology
Subjects:
systemic lupus erythematosus
human T cells
estradiol
estrogen receptors
glucocorticoid receptors
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00611/full

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