Recent Advances in Microfluidics-Based Chromatography—A Mini Review
Microfluidics-based liquid chromatography is based on the miniaturization of the different types of liquid chromatography (LC) systems (e.g., affinity, adsorption, size exclusion, ion exchange) on a microchip to perform on-chip separation of different types of analytes. On-chip chromatography finds...
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| Format: | Article |
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MDPI AG
2020-12-01
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| Series: | Separations |
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| Online Access: | https://www.mdpi.com/2297-8739/8/1/3 |
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| author | Bo Bao Zhichao Wang Dilantha Thushara Achini Liyanage Sanja Gunawardena Zaiyong Yang Shuangliang Zhao |
| author_facet | Bo Bao Zhichao Wang Dilantha Thushara Achini Liyanage Sanja Gunawardena Zaiyong Yang Shuangliang Zhao |
| author_sort | Bo Bao |
| collection | DOAJ |
| description | Microfluidics-based liquid chromatography is based on the miniaturization of the different types of liquid chromatography (LC) systems (e.g., affinity, adsorption, size exclusion, ion exchange) on a microchip to perform on-chip separation of different types of analytes. On-chip chromatography finds applications in genomics, proteomics, biomarker discovery, and environmental analysis. Microfluidics-based chromatography has good reproducibility and small sample consumption. However, the on-chip chromatography fabrication techniques are often more challenging to perform than conventional LC column preparation. Different research groups have attempted to develop different techniques to fabricate microfluidics-based LC systems. In this review, we will summarize the recent advances in microfluidics-based chromatography. |
| first_indexed | 2024-03-10T13:36:21Z |
| format | Article |
| id | doaj.art-f1e14c9308cc450a816e54b285d89c39 |
| institution | Directory Open Access Journal |
| issn | 2297-8739 |
| language | English |
| last_indexed | 2024-03-10T13:36:21Z |
| publishDate | 2020-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Separations |
| spelling | doaj.art-f1e14c9308cc450a816e54b285d89c392023-11-21T07:32:40ZengMDPI AGSeparations2297-87392020-12-0181310.3390/separations8010003Recent Advances in Microfluidics-Based Chromatography—A Mini ReviewBo Bao0Zhichao Wang1Dilantha Thushara2Achini Liyanage3Sanja Gunawardena4Zaiyong Yang5Shuangliang Zhao6State Key Laboratory of Chemical Engineering and School of Chemical Engineering, East China University of Science and Technology, Shanghai 200237, ChinaState Key Laboratory of Chemical Engineering and School of Chemical Engineering, East China University of Science and Technology, Shanghai 200237, ChinaDepartment of Chemical and Process Engineering, University of Moratuwa, Moratuwa 10400, Sri LankaDepartment of Chemical and Process Engineering, University of Moratuwa, Moratuwa 10400, Sri LankaDepartment of Chemical and Process Engineering, University of Moratuwa, Moratuwa 10400, Sri LankaGuangxi Key Laboratory of Petrochemical Resource Processing and Process Intensification Technology and School of Chemistry and Chemical Engineering, Guangxi University, Nanning 530004, ChinaState Key Laboratory of Chemical Engineering and School of Chemical Engineering, East China University of Science and Technology, Shanghai 200237, ChinaMicrofluidics-based liquid chromatography is based on the miniaturization of the different types of liquid chromatography (LC) systems (e.g., affinity, adsorption, size exclusion, ion exchange) on a microchip to perform on-chip separation of different types of analytes. On-chip chromatography finds applications in genomics, proteomics, biomarker discovery, and environmental analysis. Microfluidics-based chromatography has good reproducibility and small sample consumption. However, the on-chip chromatography fabrication techniques are often more challenging to perform than conventional LC column preparation. Different research groups have attempted to develop different techniques to fabricate microfluidics-based LC systems. In this review, we will summarize the recent advances in microfluidics-based chromatography.https://www.mdpi.com/2297-8739/8/1/3microfluidicschromatographyon-chipLC system |
| spellingShingle | Bo Bao Zhichao Wang Dilantha Thushara Achini Liyanage Sanja Gunawardena Zaiyong Yang Shuangliang Zhao Recent Advances in Microfluidics-Based Chromatography—A Mini Review Separations microfluidics chromatography on-chip LC system |
| title | Recent Advances in Microfluidics-Based Chromatography—A Mini Review |
| title_full | Recent Advances in Microfluidics-Based Chromatography—A Mini Review |
| title_fullStr | Recent Advances in Microfluidics-Based Chromatography—A Mini Review |
| title_full_unstemmed | Recent Advances in Microfluidics-Based Chromatography—A Mini Review |
| title_short | Recent Advances in Microfluidics-Based Chromatography—A Mini Review |
| title_sort | recent advances in microfluidics based chromatography a mini review |
| topic | microfluidics chromatography on-chip LC system |
| url | https://www.mdpi.com/2297-8739/8/1/3 |
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