PROSPECTS FOR PHARMACOTHERAPY OF SYSTEMIC LUPUS ERYTHEMATOSUS

The whole armory of the drugs used in rheumatology is employed to treat systemic lupus erythematosus (SLE); how- ever, most of them have not got regulatory authorities' approval and are used off-label for SLE. The successful use of a biological agent rituximab (anti-CD20 monoclonal antibodies)...

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Bibliographic Details
Main Authors: E. L. Nasonov, S. K. Solovyev
Format: Article
Language:Russian
Published: IMA PRESS LLC 2014-06-01
Series:Научно-практическая ревматология
Subjects:
Online Access:https://rsp.mediar-press.net/rsp/article/view/1946
Description
Summary:The whole armory of the drugs used in rheumatology is employed to treat systemic lupus erythematosus (SLE); how- ever, most of them have not got regulatory authorities' approval and are used off-label for SLE. The successful use of a biological agent rituximab (anti-CD20 monoclonal antibodies) and the registration of belimumab (anti-BLyS mono- clonal antibodies) for the treatment of SLE have spurred the development of novel approaches to treating this disease.
ISSN:1995-4484
1995-4492