PROSPECTS FOR PHARMACOTHERAPY OF SYSTEMIC LUPUS ERYTHEMATOSUS

The whole armory of the drugs used in rheumatology is employed to treat systemic lupus erythematosus (SLE); how- ever, most of them have not got regulatory authorities' approval and are used off-label for SLE. The successful use of a biological agent rituximab (anti-CD20 monoclonal antibodies)...

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Main Authors: E. L. Nasonov, S. K. Solovyev
Format: Article
Language:Russian
Published: IMA PRESS LLC 2014-06-01
Series:Научно-практическая ревматология
Subjects:
Online Access:https://rsp.mediar-press.net/rsp/article/view/1946
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author E. L. Nasonov
S. K. Solovyev
author_facet E. L. Nasonov
S. K. Solovyev
author_sort E. L. Nasonov
collection DOAJ
description The whole armory of the drugs used in rheumatology is employed to treat systemic lupus erythematosus (SLE); how- ever, most of them have not got regulatory authorities' approval and are used off-label for SLE. The successful use of a biological agent rituximab (anti-CD20 monoclonal antibodies) and the registration of belimumab (anti-BLyS mono- clonal antibodies) for the treatment of SLE have spurred the development of novel approaches to treating this disease.
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spelling doaj.art-f1e289ab4a2f47e185000e4c667650582023-03-22T13:45:49ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922014-06-0152331132110.14412/1995-4484-2014-311-3211880PROSPECTS FOR PHARMACOTHERAPY OF SYSTEMIC LUPUS ERYTHEMATOSUSE. L. Nasonov0S. K. Solovyev1Nasonova Research Institute of Rheumatology, Moscow, RussiaNasonova Research Institute of Rheumatology, Moscow, RussiaThe whole armory of the drugs used in rheumatology is employed to treat systemic lupus erythematosus (SLE); how- ever, most of them have not got regulatory authorities' approval and are used off-label for SLE. The successful use of a biological agent rituximab (anti-CD20 monoclonal antibodies) and the registration of belimumab (anti-BLyS mono- clonal antibodies) for the treatment of SLE have spurred the development of novel approaches to treating this disease.https://rsp.mediar-press.net/rsp/article/view/1946systemic lupus erythematosusmonoclonal antibodiesrituximabbelimumab.
spellingShingle E. L. Nasonov
S. K. Solovyev
PROSPECTS FOR PHARMACOTHERAPY OF SYSTEMIC LUPUS ERYTHEMATOSUS
Научно-практическая ревматология
systemic lupus erythematosus
monoclonal antibodies
rituximab
belimumab.
title PROSPECTS FOR PHARMACOTHERAPY OF SYSTEMIC LUPUS ERYTHEMATOSUS
title_full PROSPECTS FOR PHARMACOTHERAPY OF SYSTEMIC LUPUS ERYTHEMATOSUS
title_fullStr PROSPECTS FOR PHARMACOTHERAPY OF SYSTEMIC LUPUS ERYTHEMATOSUS
title_full_unstemmed PROSPECTS FOR PHARMACOTHERAPY OF SYSTEMIC LUPUS ERYTHEMATOSUS
title_short PROSPECTS FOR PHARMACOTHERAPY OF SYSTEMIC LUPUS ERYTHEMATOSUS
title_sort prospects for pharmacotherapy of systemic lupus erythematosus
topic systemic lupus erythematosus
monoclonal antibodies
rituximab
belimumab.
url https://rsp.mediar-press.net/rsp/article/view/1946
work_keys_str_mv AT elnasonov prospectsforpharmacotherapyofsystemiclupuserythematosus
AT sksolovyev prospectsforpharmacotherapyofsystemiclupuserythematosus