Neurolymphomatosis: Unusual Extranodal Involvement Pattern on 18F-FDG PET/CT in a Non-Hodgkin Lymphoma Recurrence

A 37-year-old woman was diagnosed with Stage IVB diffuse large-B cell lymphoma, presenting with bulky mediastinal and bone marrow involvement. She was treated with 8 cycles of R-CHOP and radiotherapy, achieving complete remission on CT. Two months latter, she presented with pain and weakness in the...

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Main Authors: Marcos Pretto Mosmann, Clarice Sprinz, Ana Amélia Raupp, Thiago Krieger Bento da Silva, Henrique Rodrigues de Abreu
Format: Article
Language:English
Published: Hospital de Clinicas de Porto Alegre ; Universidade Federal do Rio Grande do Sul (UFRGS) 2011-04-01
Series:Clinical and Biomedical Research
Subjects:
Online Access:https://seer.ufrgs.br/index.php/hcpa/article/view/18168
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author Marcos Pretto Mosmann
Clarice Sprinz
Ana Amélia Raupp
Thiago Krieger Bento da Silva
Henrique Rodrigues de Abreu
author_facet Marcos Pretto Mosmann
Clarice Sprinz
Ana Amélia Raupp
Thiago Krieger Bento da Silva
Henrique Rodrigues de Abreu
author_sort Marcos Pretto Mosmann
collection DOAJ
description A 37-year-old woman was diagnosed with Stage IVB diffuse large-B cell lymphoma, presenting with bulky mediastinal and bone marrow involvement. She was treated with 8 cycles of R-CHOP and radiotherapy, achieving complete remission on CT. Two months latter, she presented with pain and weakness in the lower limbs. The ENM, MR and the CSF analysis had shown evidence of lymphoma recurrence with initiation of intrathecal chemotherapy. Her disease continued to progress despite treatment. The following PET/CT shows multiple hypermetabolic areas, compatible with extranodal disease and poor response to therapy, allowing change to R-ICE and autologous stem cell treatment.
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spelling doaj.art-f1e3aa8a34d748ab8a990332122649b02022-12-22T02:48:50ZengHospital de Clinicas de Porto Alegre ; Universidade Federal do Rio Grande do Sul (UFRGS)Clinical and Biomedical Research2357-97302011-04-0131110970Neurolymphomatosis: Unusual Extranodal Involvement Pattern on 18F-FDG PET/CT in a Non-Hodgkin Lymphoma RecurrenceMarcos Pretto Mosmann0Clarice Sprinz1Ana Amélia Raupp2Thiago Krieger Bento da Silva3Henrique Rodrigues de Abreu4Serviço de Medicina Nuclear Hospital de Clínicas de Porto AlegreServiço de Medicina Nuclear e PET/CT Hospital Mãe de DeusServiço de Medicina Nuclear e PET/CT Hospital Mãe de DeusServiço de Radiologia Hospital Mãe de DeusServiço de Radiologia Hospital Mãe de DeusA 37-year-old woman was diagnosed with Stage IVB diffuse large-B cell lymphoma, presenting with bulky mediastinal and bone marrow involvement. She was treated with 8 cycles of R-CHOP and radiotherapy, achieving complete remission on CT. Two months latter, she presented with pain and weakness in the lower limbs. The ENM, MR and the CSF analysis had shown evidence of lymphoma recurrence with initiation of intrathecal chemotherapy. Her disease continued to progress despite treatment. The following PET/CT shows multiple hypermetabolic areas, compatible with extranodal disease and poor response to therapy, allowing change to R-ICE and autologous stem cell treatment.https://seer.ufrgs.br/index.php/hcpa/article/view/18168PETPET/CTNeurolymphomatosisLymphoma
spellingShingle Marcos Pretto Mosmann
Clarice Sprinz
Ana Amélia Raupp
Thiago Krieger Bento da Silva
Henrique Rodrigues de Abreu
Neurolymphomatosis: Unusual Extranodal Involvement Pattern on 18F-FDG PET/CT in a Non-Hodgkin Lymphoma Recurrence
Clinical and Biomedical Research
PET
PET/CT
Neurolymphomatosis
Lymphoma
title Neurolymphomatosis: Unusual Extranodal Involvement Pattern on 18F-FDG PET/CT in a Non-Hodgkin Lymphoma Recurrence
title_full Neurolymphomatosis: Unusual Extranodal Involvement Pattern on 18F-FDG PET/CT in a Non-Hodgkin Lymphoma Recurrence
title_fullStr Neurolymphomatosis: Unusual Extranodal Involvement Pattern on 18F-FDG PET/CT in a Non-Hodgkin Lymphoma Recurrence
title_full_unstemmed Neurolymphomatosis: Unusual Extranodal Involvement Pattern on 18F-FDG PET/CT in a Non-Hodgkin Lymphoma Recurrence
title_short Neurolymphomatosis: Unusual Extranodal Involvement Pattern on 18F-FDG PET/CT in a Non-Hodgkin Lymphoma Recurrence
title_sort neurolymphomatosis unusual extranodal involvement pattern on 18f fdg pet ct in a non hodgkin lymphoma recurrence
topic PET
PET/CT
Neurolymphomatosis
Lymphoma
url https://seer.ufrgs.br/index.php/hcpa/article/view/18168
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AT anaameliaraupp neurolymphomatosisunusualextranodalinvolvementpatternon18ffdgpetctinanonhodgkinlymphomarecurrence
AT thiagokriegerbentodasilva neurolymphomatosisunusualextranodalinvolvementpatternon18ffdgpetctinanonhodgkinlymphomarecurrence
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